Data Registration

The method is based on the international standard ISO 4053/IV. A small amount of the radioactive tracer is injected instantaneously into the flare gas flow through e.g. a valve, representing the only physical interference with the process. Radiation detectors are mounted outside the pipe and the variation of tracer concentration with time is recorded as the tracer moves with the gas stream and passes by the detectors. A control, supply and data registration unit including PC is used for on site data treatment... 

The REGISTER application can also be easily modified to meet the requirements of other organizations, which may use it for corporate data registration and storage as a central depository of proprietary chiral separations. 

Fig. 4-2. Screen of REGISTER (data registration tool for enantioseparations).

Here, the rinsing and other preparation steps are included in the time scale. The type of data registration may be different in other commercial instruments. 

C. Eggeling, S. Berger, L. Brand, J.R. Fries, J. Schaffer, A. Volkmer, C.A. Seidel, Data registration and selective single-molecule analysis using multiparameter fluorescence detection, J. Biotechnol. 86, 163 (2001)... 

For the measurement of the impedance, a modem impedance spectrometer provides automatic data registration over at least five decades of frequency. With this equipment it... 

The data exchange goes through three-state bidirectional transceiver 74LS244 (A65, A72). The data from the upper four lines between transceiver and RAM can be stored in latch 74LS373 (A75) in order to avoid false data registration in some phases of the programme. 

FIFRA Sections 3 and 4 pertain to registration and reregistration of pesticides, with clearly defined data requirements as outlined in Tide 40 of the US. Code of federal Regulations (51). About 120 different studies are Hsted, most of which are to be done on technical-grade active ingredients (TGAIs). 

Subdivision O guidelines for residue chemistry data were originally pubHshed by the EPA in 1982. These have been supplemented to improve the rate of acceptance by EPA reviewers of the many reports submitted by registrants in support of tolerances for pesticides in foods. The residue chemistry studies most frequently rejected include metaboHsm in plants, food processing (qv) studies, and studies on storage stabHity of residues in field samples (57). AH tolerances (maximum residue levels) estabHshed under FIFRA are Hsted in 40 CFR under Sections 180 for individual pesticides in/on raw agricultural commodities, 180 for exemptions from tolerances, 185 for processed foods, and 186 for animal feeds. 

Japan. In Japan, registration of dmgs for aquatic species requires the same data as those required for dmgs on other animals. The Ministry of Agriculture, Eorests, and Eisheries and the Ministry of Welfare control the use of chemicals in aquaculture in Japan (17). The preclinical data requirements include product chemistry, toxicity (acute, subacute, special) using rats and mice, safety to target animals, and metaboHsm. The requirements for clinical data include avadabiHty and residues. As of July 1990, more chemicals were registered for aquacultural use in Japan than in any other country (Table 4). 

The University of Idaho and USFWS, with funds from the Bonneville Power Administration, are also gathering data for registration of erythromycin. Erythromycin is intended for control of bacterial kidney disease in salmonid fingerlings that can also be transmitted by broodstock to the eggs (9). If research is completed on schedule and data indicate that the compound is safe and effective, registration is scheduled for 1994 (see Antibiotics, MACROLIDES). 

Registration of a new chemical substance in the United States and Japan requkes similar comprehensive sets of data, although there are some differences. Obtaining all the data for a full registration can be time-consuming and costiy. In 1989 it cost approximately 150,000 and took about a year to register a new substance in Europe. 

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