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Darunavir

Zidovudine Didanosine Stavudine Lamivudine Abacavir Tenofovir Emtricitabine Nevirapine Efavirenz TMC125 Saquinavir Indinavir Lopinavir Fosamprenavir Atazanavir Tipranavir Darunavir Raltegravir Elvitegravir Enluvirtide Maraviroc Vicriviroc Bevirimat... [Pg.335]

Darunavir (DRV) 300 mg tablet DRV 600 mg + Use with caution in Should be given Skin rash (has a sulfonamide CYP3A4 inhibitor and... [Pg.1264]

At Step 6, large molecules of the viral proteins are made. Protease cleaves the large protein molecules into smaller pieces. Another drug, a protease inhibitor (darunavir, Prezista), is used to inhibit the protease, thus stopping the formation of new viruses. [Pg.37]

TC Lamivudine ABC Abacavir d4T Stavudine ddC Zalcitabine ddl Didanosine TDF Tenofovir ZDV Zidovudine, also abbreviated as AZT FTC Emtricitabine NVP Nevirapine DLV Delavirdine EFV Efavirenz RTV, r Ritonavir Pl/r Ritonavir boosted protease inhibitor SQV Saquinavir IDV Indinavir LPV Lopinavir NEV Nelfinavir APV Amprenavir ATV Atazanavir DRV Darunavir... [Pg.550]

Darunavir PI2 600 mg bid with ritonavir 100 mg bid Take with food Diarrhea, headache, nausea, rash, hyperlipidemia, t liver enzymes, t serum amylase Avoid in patients with sulfa allergy. See footnote 4 for contraindicated medications... [Pg.1074]

Etravirine Delavirdine, efavirenz, lopinavir/ritonavir, nevirapine, ritonavir, tipranavir Darunavir, saquinavir, tenofovir... [Pg.1077]

Indinavir Delavirdine, nelfinavir, ritonavir, zidovudine, darunavir Fosamprenavir, didanosine, efavirenz, etravirine, nevirapine... [Pg.1077]

Lopinavir Delavirdine, indinavir, ritonavir, darunavir Fosamprenavir, efavirenz, nelfinavir, nevirapine, tenofovir... [Pg.1077]

Darunavir is licensed as a PI to be -administered with ritonavir in treatment-experienced patients with resistance to other Pis. [Pg.1081]

Symptomatic adverse effects of darunavir include diarrhea, nausea, headache, and rash. Laboratory abnormalities include dyslipidemia (though possibly less frequent than with other boosted PI regimens) and increases in amylase and hepatic transaminase levels. Liver toxicity, including severe hepatitis, has been reported in some patients taking darunavir the risk of hepatotoxicity may be higher for persons with HBV, HCV, or other chronic liver disease. [Pg.1081]

Darunavir contains a sulfonamide moiety and should be used cautiously in patients with sulfonamide allergy. [Pg.1081]

Darunavir both inhibits and is metabolized by the CYP3A enzyme system, conferring many possible drug-drug interactions (Table 49-3). In addition, the co-administered ritonavir is a potent inhibitor of CYP3A and CYP2D6, and an inducer of other hepatic enzyme systems. [Pg.1081]

Darunavir is a nonpeptide second-generation protease inhibitor of HIV-1. In combination with ritonavir, it is superior to lopinavir plus ritonavir. Darunavir is a selective inhibitor of the cleavage of HIV-encoded gag-pol polyproteins in infected cells,... [Pg.192]

Qotet B, Bellos N, Mohna JM, Cooper D, et al. 2007. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2 A pooled subgroup analysis of data from two randomized trials. Lancet. 369 1169-1178. [Pg.197]

MacArthur RD. 2007. Darunavir Promising initial results. Lancet. 369 1143-1144. [Pg.199]


See other pages where Darunavir is mentioned: [Pg.3]    [Pg.89]    [Pg.89]    [Pg.89]    [Pg.92]    [Pg.103]    [Pg.104]    [Pg.305]    [Pg.316]    [Pg.341]    [Pg.1276]    [Pg.586]    [Pg.617]    [Pg.455]    [Pg.506]    [Pg.515]    [Pg.516]    [Pg.517]    [Pg.587]    [Pg.619]    [Pg.126]    [Pg.550]    [Pg.1077]    [Pg.1081]    [Pg.1088]    [Pg.126]    [Pg.192]    [Pg.193]   
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Clarithromycin Darunavir

Darunavir Efavirenz

Darunavir Foods

Darunavir Indinavir

Darunavir Itraconazole

Darunavir Ketoconazole

Darunavir Lopinavir

Darunavir Nevirapine

Darunavir Omeprazole

Darunavir Ranitidine

Darunavir Rifabutin

Darunavir Ritonavir

Darunavir Saquinavir

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Diarrhea darunavir

Protease inhibitors darunavir

Rashes darunavir

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