Daily allowance chromium

Four essential elements, Ft, O, C, and N, comprise more than 99 atom % and about 96 wt % of the human body. These 4 and 14 other essential elements occur among the first 30 elements (through zinc) of the periodic table. (Uncertainties surround the status of chromium (see Chromium Biological Relevance). ) Three heavier trace elements Se, Mo, and I are also essential in humans. For 17 tabulated essential elements, Table 1 shows the predominant elemental form at pH 7, typical adult concentrations in the blood plasma or serum, the approximate amount found in a 70-kg adult, and a recommended adult daily allowance. In addition to... 

Trivalent chromium compounds (chromium chloride, chromium nicotinate, and chromium picohnate) are used by patients to enhance weight loss, to increase lean body mass, or to improve glycemic control. Drug histories should include attention to the use of over-the-counter nutritional supplements often regarded as harmless by the pubhc and lay media. The recommended daily allowance of chromium picolinate is 50-200 micrograms, but information about its toxicity is limited. 

Toxicity secondary to chronic ingestion of 6-12 times the recommended daily allowance of over-the-counter chromium picolinate has been reported (22). 

Recommended Daily Allowance of Chromium Conserving the Body s Supply of Chromium Toxicity... 

RECOMMENDED DAILY ALLOWANCE OF CHROMIUM. A normal healthy adult loses about 1 meg (microgram) of chromium daily in his/her urine. The dietary intake of chromium needed to replace this loss ranges from 4 meg of GTF-chromium in brewers yeast (as much as 25% of this form may be absorbed) to 200 meg of chromium from an inorganic salt (as little as 0.5% of this form may be absorbed). 

The Committee on Dietary Allowances, Food and Nutrition of the National Research Council has recommended an estimated safe and adequate daily dietary intake of 50-200 pg/day for adults based on the absence of chromium-deficiency signs in the major part of the U.S. population consuming an average of 50 pg chromium/day (NRC 1989). ATSDR has adopted the upper range of the estimated safe and adequate daily dietary intake of 200 pg/day as provisional guidance for oral exposure to chromium(VI) and chromium(III). 

Recommended dietary allowances for a male adult (daily intake, in foods and food supplements) of some nutrients, usually the amounts estimated as needed to prevent overt manifestation of deficiency disease in most persons. For the substances listed in smaller amounts the optimum intake, leading to the best of health, may be somewhat greater. Not shown, but probably or possibly required, are the essential fatty acids, />aminobenzoic acid, choline, vitamin D, vitamin K, chromium, manganese, cobalt, nickel, zinc, selenium, molybdenum, vanadium, tin, and silicon. 

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