Graft Dacron

Recent results [85] from carotid replacement by HEMA-STY-coated dacron graft (3 mm ID) were noteworthy. Luminal surface was very clean after 372-day implantation. 

To test this hypothesis, the Dacron graft of Fig. 6 was replaced by a coated graft similar to the one described in Section II,G, and the indium-111 platelet accretion study was repeated in the absence of the Fig. 6 infusion assembly. The half that had not been treated with NO accumulated... 

Compounds (27.4) and (27.5) were evaluated in an in vivo irterio-venous shunt thrombosis model in baboons, ind both compounds at 1 p-g min were found to be iffective in blocking platelet deposition, as monitored in eal time by accumulation of Indium oxine-labelled laboon platelets on a dacron graft. Encouraged by these esults, compounds (27.4) and (27.5) were further evaluated... 

Hydrophobic coatings composed of silicon- and fluorine-containing polymeric materials as well as polyurethanes have been studied because of the relatively good clinical performances of Silastic , Teflon , and polyurethane polymers in cardiovascular implants and devices. Polymeric fluorocarbon coatings deposited from a tetrafluoroethylene gas discharge have been found to greatly enhance resistance to both acute thrombotic occlusion and embolization in small diameter Dacron grafts. 

Figure 2.11 Patient had undergone a femoral peroneal bypass using a Dacron graft (large arrow) with a distal arteriovenous fistula (dAVF) constructed at the distal anastomosis. The peroneal artery (P) runoff is depicted by an arrow and smaller arrows point to the venous return via the fistula that removes the overload to the distal circulation, enabling improved graft patency.

Wukasch DC, Cooley DA, Bennett JG, Gontijo B and Bongiorno FP. Results of a new Meadox Cooley Double velour Dacron graft for arterial reconstruction. /. Cardiovasc. Surg. 20 249-260,1979. 

In 2005 Blanchemain et al. immersed PET vascular prostheses into a solution containing a polycarboxylic acid, a cyclodextrin (CD) (Fig. 13.17) and a catalyst, and placed them into a thermofixation oven before impregnation with an antibiotic solution (vancomycin). They demonstrate the feasibility of coating CDs onto vascular Dacron grafts and there was no toxicity with the different cyclodextrins. A linear release of antibiotics was depicted over 50 days, demonstrating also that cyclodextrin grafting was an efficient dmg delivery system [49]. 

PTFE) layer that would seal the hole in the vessel wall. The Wallgraft (Boston Scientific) has a woven Dacron graft material and although this is more porous, it will still effectively seal a hole and prevent further bleeding. 

Hunter, G.C., Schmidt, S.P., Sharp, W.V., and Malindzak, G.S. 1983. Controlled flow studies in 4 mm endothelialized Dacron grafts. Trans. ASAIO 29 177-182. 

Eiderg JP, Roder 0, Stahl-Madsen M, Eldrup N, Qvarfordt P, Laursen A, et al. Fluropoly-mer-coated Dacron graft versus P i EE grafts for femorofemoral crossover by pass. Eur J Vase Endovasc Surg 2006 32 431-8. 

Synthetic materials used in the stents development such as PET or PTFE have failed in coronary revascularization [128]. Dacron grafts lead to thrombosis and neointimal thickening in low blood flow. The PTFE grafts also fail owing to surface thrombogenicity... 

Thrombus at the junction of a rough (Dacron graft) and smooth (Silastic) surface. Although a smooth neointima is formed on the graft (below the suture line), thrombus is evident at the graft Silastic junction. 

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