Cyanogenic glucosides structure

Due to homologies in structures and biosynthesis, some minor groups of natural products seem to be related to cyanogenic glucosides. These compounds, i.e. cyanogenic lipids, nitrile- and nitro-compounds, are briefly presented in this chapter. 

Plants are the best organic chemists in nature as evidenced by their ability to synthesize all necessary carbon compounds with carbon dioxide as the sole carbon source and by their ability to synthesize a vast number of natural products. Currently, structures for more than 100,000 different natural products isolated from plants are known, and with time this number will increase into millions. Natural products are classified as phytoanticipins, phytoalexins, and/or attractants. In the last decade, the majority of the biosynthetic pathways responsible for natural product synthesis have been shown to include P450s as key enzymes. Such pathways include the biosynthetic pathways for cyanogenic glucosides, glucosinolates, isoflavonoids, and... 

Cyanogenic Glucosides with a Cyclopentenoid Ring Structure... 

Brimer, L., S. Brogger-Christensen, J. W. Jaroszewski, and F. Nartey, Structural elucidation and partial synthesis of 3-hydroxyheterodendrin, a cyanogenic glucoside from Acacia sieberiana var. woodii. Phytochemistry, 20,2221-2223 (1981). 

Fig.1 The general structure of cyanogenic glucosides (a) and glucosinolates (b) structure. In (b), the R group is derived from amino acids and is highly variable. It may be aliphatic, aromatic or heterocyclic...

FIGURE 17.5 Chemical structure of antinutritional factors associated with some cereal grains, (a) Cyanogenic glucosides. (b) Goitrogens. 

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