Cupric acetate monohydrate

Chemical Designations - Synonyms Acetic Acid Cupric Salt Crystallized Verdigris Cupric Acetate Monohydrate Neutral Verdigris Chemical Formula Cu(C2H302)2 H20. 

Recently, the required heteroaromatic organozinc halides for the Negishi reaction have also been prepared using microwave irradiation [23]. Suna reported that a Zn - Cu couple (activated Zn), prepared using a slightly modified LeGoff procedure from Zn dust and cupric acetate monohydrate, allowed the smooth preparation of (3-pyridinyl)zinc iodide and (2-thienyl)zinc iodide... 

Hydrochloric acid, 37%, Merck, code 317, or equivalent Stannous chloride dihydrate, Merck, code 7815, or equivalent Cupric acetate monohydrate, Merck, code 2711, or equivalent Lead acetate trihydrate, Merck, code 7372, or equivalent... 

Creosol, 33, 17 Crotonaldehyde, 33, IS 34, 29 diethyl acetal, 32, 5 Cupric acetate monohydrate, 36, 77 Cuprous oxide-silver oxide, 36, 36, 37 Cyanamide, 34, 67 36, 8 Cyanoacetamide, 32, 34 Cyanoacetic acid, 31, 25 Cyanoacetylurea, 37, 16 >-Cyanobenzaldehyde, 30, 100 >-Cyanobenzaldiacetate, 36, 59 3-Cyano-5,6-dimethyl-2(l)-pyridone, 32,34 N-2-Cyanoethylaniline, 36, 6 N-2-Cyanoethyl- -anisidine, 36, 7 Cyanoethylation, of aniline, 36, 6 of ethyl phenylcyanoacetate, 30, 80 N-2-Cyanoethyl-m-chloroaniline, 36, 7 Cyanogen, 32, 31 Cyanogen iodide, 32, 29 Cyanogen iodide, complex with sodium iodide, 32, 31... 

B. Phenylglyoxal. The phenylglyoxal hemimercaptal prepared as described in procedure A (69-74 g.) is dissolved in 400 ml. of warm chloroform, and 60 g. (0.30 mole) of powdered cupric acetate monohydrate is added in one portion to the well-stirred solution. The mixture is stirred at room temperature for 1 hour the solids are removed by suction filtration and washed with two 75-ml. portions of chloroform. The combined chloroform filtrate and washings are shaken in a separatory funnel with 75 ml. of water 20 g. of powdered sodium carbonate is added in small portions to the funnel, and the chloroform solution is shaken with the neutralized aqueous solution. (Cautionl Carbon dioxide is evolved.) The aqueous layer is separated and extracted with four 30-ml. portions of chloroform. The chloroform solutions are combined and dried with anhydrous magnesium sulfate, and the chloroform is removed under reduced pressure. The residue is fractionally distilled under reduced pressure to yield 43-49 g. (64-73%, based on ethyl benzoate) of anhydrous phenylglyoxal as a yellow liquid, b.p. 63-65° (0.5 mm.). 

Cupric acetate monohydrate A. R. available from Fisons Scientific Apparatus Ltd. (Loughborough, England) was employed by the submitters. The checkers used both Baker Analytical Reagent and Fisher A.C.S. certified cupric acetate monohydrate. Small portions were finely ground with a mortar and pestle. 

Commercially available crystalline cupric acetate monohydrate was used. A large excess of cupric acetate does not improve the yield. Small catalytic amounts can be used if the cupric salt is continually regenerated by passage of oxygen through the reaction mixture, but the procedure is much slower. 

To a saturated solution of 5.5 g. (0.028 mole) of finely powdered cupric acetate monohydrate (Note 1) in 20 riil. of a 1 1 by volume pyridine-methanol mixture (Notes 2, 3, 4, and 5) contained in a 50-ml. round-bottomed flask fitted with a reflux condenser is added 2.0 g. (0.0196 mole) of phenylacetylene (Note 6). The deep-blue suspension becomes green when heated under reflux. After 1 hour of heating, the solution is cooled (Note 7) and added dropwise to 60 ml. of 18N sulfuric add, with stirring and external cooling in an ice-salt freezing mixture (Note 8). The resulting white suspension is extracted with three 25-ml. portions of ether, and the combined ethereal extracts are washed with 15 ml. of... 

Cumyl Hydroperoxide Cupric Acetate Monohydrate Cupric Arsenite Cupric Bromide, Anhydrous Cupric Chloride Dihydrate Cupric Fluoborate Solution Cupric Green Cupricin... 

A 250-mL, one-necked, round-bottomed flask is equipped with a magnetic stirrer and a reflux condenser protected by a calcium chloride drying tube. Into the flask are placed 30.0 g (0.14 mol) of di-tert-butyl malonate (Note 1) 8.4 g (0.28 mol) of paraformaldehdye (Note 2), 1.4 g (0.014 mol) of potassium acetate, 1.4 g (0.007 mol) of cupric acetate monohydrate, and 70 mL of glacial acetic acid. The resulting green-white suspension is placed in an oil bath preheated to 90-100°C and stirred for 2 hr (Note 3). The reaction mixture is allowed to cool to room temperature, and the reflux condenser is replaced with a short-path distillation apparatus, the vacuum outlet of which 1s connected in sequence to a trap cooled in acetone-dry ice, a potassium hydroxide trap, another trap cooled in acetone-dry ice, and a vacuum pump. The receiving flask 1s cooled in acetone-dry 1ce, and the system is evacuated over approximately 1 hr to remove acetic acid and other volatile material... 

Cupric acetate monohydrate Acetic acid, copper(2+) salt, monohydrate (8,9) (6046-93-1)... 

The effect of additives in altering the catalyst environment has been studied by Wright and Weller (6). Chelation is known to alter the oxidation-reduction properties of ions and therefore could be expected to alter the activation of hydrogen. Ethylene diamine and ethylene diamine tetra-acetic acid inhibit both the rate and extent of reduction of quinone and cupric acetate monohydrate in quinoline solution at 100°. The production of metallic copper is related to the presence of organic material. 

It is of considerable interest that some 14 years after Calvin postulated these structures, van Niekerk and Schooling (8) showed by X-ray analysis that cupric acetate monohydrate, Cu(OAc)i.HjO, exists in the solid as dimeric molecules, the two copper ions being joined by four bridging acetate groups. The copper-copper distance in the dimer is only 2.64 A., as compared with 2.56 A. in the metal. 

Weigh the cupric acetate monohydrate in an Erlenmeyer flask. Dissolve cupric acetate monohydrate in glacial acetic acid (5 mL). 

A 500-ml. three-necked flask equipped with a stirrer, reflux condenser, and thermometer is charged with 255 g. (2.0 moles) of o-chloroaniline, 106 g. (2.0 moles) of acrylonitrile, and 10.2 g. (4.0% by weight of the amine) of cupric acetate monohydrate (Note 1). The mixture is then stirred and heated to reflux, beginning at about 95°. Refluxing is continued for 3.0 hours (Note 2), with the pot temperature rising to about 130° (Note 3). 

Catalyst, alumina, 34, 79, 35, 73 ammonium acetate, 31, 25, 27 boron tnfluonde etherate, 38, 26 copper chromite, 31, 32, 36, 12 cupric acetate monohydrate, 38, 14 cuprous oxide silver oxide, 36, 36, 37 ferric nitrate, hydrated, 31, 53 phosphoric acid, 38, 25 piperidine, 31, 35 piperidine acetate, 31, 57 Raney nickel, 36, 21, 38, 22 sulfuric acid, 34, 26 Catechol, 33, 74 Cetylmalonic acid, 34, 16 Cetylmalonic ester, 34,13 Chlorination, by sulfuryl chloride, 33, 45, 37, 8... 

Preformed Ethvnvlation Catalyst. Into a 500-mL round-bottomed flask equipped with a magnetic stir bar, reflux condenser and nitrogen bubbler was placed palladium chloride (1.77 g, 10 mmol), di-n-propylamine (100 mL) and triphenylphosphine (15.74 g, 60 mmol). The resulting slurry was boiled for two hr after which time the brown palladium chloride had been consumed and the yellow bis(triphenylphosphine) palladium(II) chloride had formed. The slurry was cooled and cupric acetate monohydrate (1.99 g, 10 mmol) was added in one portion and the slurry boiled for one hr longer. After cooling, the solvent was removed by rotary evaporation and then finally under high vac-... 

Oxidative coupling of 1,5-hexadiyne to cyclooctadeca-l,3,7,9,l3,I5-liexaytte, A 6-1. three-necked, round-bottomed flask fitted with a stirrer having two 7.5-cm. paddles 9 cm. apart, a reflux condenser, and a 50O-ml. dropping funnel (with a pressure equalizing arm) is charged with 600 g. of cupric acetate monohydrate and 3.81. of... 

OXIDATION, REAGENTS Dimethylsulf-oxide-Acetic anhydride. 1-Amyl hydroperoxide. N-Bromosuccinimide. Ceric ammonium nitrate. Chloramine. o-Chlo-ranil. 1-Chlorobenzotriazole. N-Chloro-succinimide-Dimethyl Sulfide. Chromic acid. Chromic anhydride. Chromyl chloride. Cobalt(ll) acetate. Cupric acetate monohydrate. Cupric nitrate-Pyridhic complex. 2,3-Dichloro-5,6-dicyano-l, 4-benzoquinonc. Dicyclohcxyl-18-crown-... 

In a 100-mL flask fitted with a reflux condenser are placed 0.1 g (0.0005 mol) of cupric acetate monohydrate (as a catalyst), 5 g (0.0625 mol) of ammonium nitrate, 10.6 g (0.05 mol) of benzoin, and 35 mL of 80% aqueous acetic acid. The mixture is heated with occasional shaking of the flask. Soon a vigorous evolution of nitrogen commences. After a 1.5-h reflux, the solution is cooled and seeded with a crystal of benzil (or by scratching the walls of the flask with a glass rod) until crystallization takes place. Water is added to the mixture to precipitate the residual benzil. The crystals are filtered with suction and washed with water containing about 20% of ethanol. The yield of benzil is quantitative. The melting point of the product after recrystallization from 70% ethanol is 95 °C. 

FIG. 25.14. (a) Crystal structure of Cu(HCOO)j. 4 H2O, (b) dimeric units in cupric acetate monohydrate, (c) chain structure of cupric succinate dihydrate. 

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