Cucurbita maxima

Azevedo-Meleiro CH and Rodriguez-Amaya DB. 2007. Qualitative and quantitative differences in carotenoid composition among Cucurbita moschata, Cucurbita maxima, and Cucurbita pepo. J Agric Food Chem 55 4027 1033. 

T. B. Osborne and S. H. Clapp. Hydrolysis of the Crystalline Globulin of the Squash Seed (Cucurbita maxima). Amer. J. Physiol., 1907, 19, 475-481. 

N.A. Cucurbita maxima L. Linoleic acid, oleic acid, cucurbitacins, vitamins.99 Against tapeworms in pregnant women and in children, treat nephritis, urinary problems. 

Anagalis arvensis, Cucurbita maxima Curcuma longa, Santalum album Curcuma aromatica Quercus robur Prunus mume Jatropha gospiifolia... 

Rorippa nasturtium-aquaticum, Cucurbita maxima, Ficus carica, Glycine max, Medicago sativa, Rosa rugosa, R. acicularis, Ziziphus jujuba Lythrum salicaria Vitex labrusca, V. agnus-castus... 

Figure 5. The metabolic pathway beyond GAn-aldehyde for pumpkin endosperm ("Cucurbita maxima). Heavy arrows represent the preferred pathway based on relative rates of conversion and levels of metabolites.

Biosynthesis of gibberellins Aip, A, Apl, Agg, and A07 hy a cell-free system from Cucurbita maxima." Phytochemistry, 1974, 13, ll+33-lUto. 

The seeds of squash plants are rich in a family of trypsin and chymotrypsin inhibitors that are approximately 35 amino acids in size and have been extensively investigated not only for their enzyme inhibitory activity, but also because they are very stable mini-protein scaffolds with applications in protein engineering. The best studied examples are Ecballium elaterium trypsin inhibitor (EETI-II) and Cucurbita maxima trypsin inhibitor (CMTI). Both X-ray and NMR have been used to characterise their structures, which incorporate a cystine-knot motif formed by three conserved disulphide bonds.93 We will describe this motif in more detail in a later section describing the plant cyclotides. 

Cucurbita maxima (squash) (Cucurbitaceae) [seed] Pumpkin fruit trypsin inhibitor (PFTI) (8 kDa 0 Cys) Trypsin [440, 442]... 

Vietnamese squash) which are cyclic peptides (cyclotides) [541]. The small size, exceptional stability and protease inhibitor potency of these cyclic squash family PIPs make them potentially very useful lead compounds and structural scaffolds for pharmaceutical development [541], The structures of various squash family PIPs have been determined, namely those of Cucurbita maxima CMTI-I [544, 545], Cucurbita pepo CPTI-n [545], Momordica charantia MCTI-A [556, 557] and the cyclotide Momordica cochinchinensis McoTI-U [541]. The linear squash PIP structures involve anti-parallel P-strand elements beneath a loop which contains the protease binding site [544, 545, 556, 557]. 

The biosynthesis pathway of GAs in plants has long been studied since their discovery as endogenous growth regulators. There have been two key approaches to unravel the biosynthetic routes and identify the genes encoding the biosynthetic enzymes. First, a cell-free system prepared from immature seeds of dicotyledonous species such as Marah macrocarpus and Cucurbita maxima allowed researchers to purify and characterize the GA... 

Cucurbita phloem lectin Cucurbita maxima (pumpkin, ... 

Cucurbita CMTI-III Cucurbita maxima (pumpkin) Xa [23], Xlla [70nM], KAL... 

Yamaguchi, S., Saito, T., Abe, H., Yamane, H., Murofushi, N. and Kamiya, Y. (1996) Molecular cloning and characterization of a cDNA encoding the gibberellin biosynthetic enzyme ent-kaurene synthase B from pumpkin (Cucurbita maxima L). Plant., 10, 203-13. 

Squash are frost-tender annuals grown for their fleshy fruit. Summer squash, such as zucchini, are eaten before the seeds and rinds harden. Winter squash are harvested after the fruit is mature. The name pumpkin is used for some winter squash. Species include Cucurbita maxima, C. mixta, C. moschata, and C. pepo. 

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