Crimea Dry Steppe region of the biosphere

Furthermore, it is necessary to evaluate the isolated and complex physiological effects of some toxic and essential metals on such endpoints (biomarkers) as the neurobehavioral and psycho-physiological parameters and also cardiovascular and immune parameters. The effect depends on metals content in the human body. Moreover, it depends on physiological effects, not only the daily intake. 

The results of the investigation of 58 adult persons who live on industry territory of North Crimea and 60 male teenagers at age 15 years and 84 children (2-14 years) in the Simferopol city showed that the children are more sensitive to the relatively low level of heavy metal concentrations than the adult (Evstafyeva et al., 2002). It is known that many toxic metals have neurotoxic effects (Arezzo et al., 1985). It was also shown that the effects of central and autonomous nervous systems of different 

Examination of the central nervous system was carried out on a basis of recording 30 indices of electroencephalograms (EEG) and evoked potentials (EP). This method has been earlier described in detail (Pavlenko et al., 2000). The state of autonomous nervous system was assessed by variability of cardio intervals (Vein, 1991). 

The content of heavy metals in human hair was defined by the Roentgen-fluorescent method (non-toxic metals) in the laboratory of analytical chemistry and toxic substances at Institute of the Occupational Medicine of Scientific Medical Academy of Ukraine. 

The results have been statistically processed by means of Spearman s non-parametrical correlation analysis and by multiple regression analysis to assess the complex effects induced by toxic and essential elements (Evstafyeva, Slusarenko, 2003 Evstafyeva et al., 2004). 

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Case study of interactions between human health indexes and pollution in Crimea Dry Steppe region of the biosphere... 

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