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Unsaturated organic molecules, coupling reactions with

B. Coupling Reactions with Unsaturated Organic Molecules. 173... [Pg.137]

The synthesis of enantiomerically pure compounds is the challenging problem for organic chemists. The synthesis becomes obsolete if the intermediates produce racemic mixtures. The problem is particularly acute when the asymmetric centers do not reside in a rigid cyclic or polycyclic framework. To be able to carry out efficient syntheses of complex molecules, chemists have to control the sense of chirality at each chiral center as it is introduced in the course of synthesis. Monoalkyl- or dialkyl-boranes exhibit a remarkable chemo-, stereo-, and regioselectivity for the hydroboration of unsaturated compounds. This property, coupled with the capability for asymmetric creation of chiral centers with chiral hydroboration agents, makes the reaction most valuable for asymmetric organic synthesis. In some of the cases, however, this has been achieved by diborane itself as shown in the synthesis of monensin by Kishi et al. A stereospecific synthesis of its seven carbon. component has been accomplished by two hydroboration reactions (Eq. 129) 209. ... [Pg.77]


See other pages where Unsaturated organic molecules, coupling reactions with is mentioned: [Pg.211]    [Pg.2864]    [Pg.4917]    [Pg.483]    [Pg.555]    [Pg.2863]    [Pg.4916]    [Pg.366]    [Pg.515]    [Pg.137]    [Pg.173]    [Pg.193]    [Pg.195]    [Pg.300]    [Pg.194]    [Pg.82]    [Pg.105]    [Pg.101]    [Pg.146]    [Pg.234]    [Pg.4108]    [Pg.298]    [Pg.273]    [Pg.153]    [Pg.356]    [Pg.375]    [Pg.521]    [Pg.4107]    [Pg.233]    [Pg.105]    [Pg.525]    [Pg.438]    [Pg.251]    [Pg.425]    [Pg.70]    [Pg.295]    [Pg.304]    [Pg.50]    [Pg.2625]    [Pg.50]    [Pg.2624]   
See also in sourсe #XX -- [ Pg.173 , Pg.174 , Pg.175 , Pg.176 , Pg.177 , Pg.178 , Pg.179 , Pg.180 , Pg.181 , Pg.182 , Pg.183 , Pg.184 , Pg.185 , Pg.186 , Pg.187 , Pg.188 , Pg.189 , Pg.190 , Pg.191 ]




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Coupling Reaction with

Molecules organization

Molecules, coupling

Organic reactions with

Reaction with unsaturated

Reactions unsaturated

Unsaturated molecules

Unsaturated organic molecules

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