Corynanthe yohimbe

Yohimbine (36) is a well-known and reasonably available alkaloid from Corynanthe yohimbe, inter alia. For this reason, and partly because of its intrinsic pharmacological activity (including reputed aphrodisiac activity), chemists have frequently studied its properties. Oppenauer oxidation is usually attended by saponification and decarboxylation in this series, and yohimbone (37) is the product. Wolf-Kischner reduction to yohimbane (38), followed by sodium hydride mediated alkylation, leads to the analgesic agent, mimbane (39). °... 

Rauwolfia serpentina L. Boith., Gentianales and Corynanthe yohimbe K, Schum., Rubiales, Ang. from S Asia... 

YOHIMBE -- Corynanthe yohimbe. Family Rubiaceae (Madder family). 

Material Yohimbine is one of several indole-based alkaloids found in Corynanthe yohimbe, Rauwolfia serpentina, and several other plants. 

Yohimbine is a major carboline alkaloid in the bark of Pausinystalia species, such as Pausinystalia yohimbe (Corynanthe yohimbe), Pausinystalia macrocerus, Pausinystalia paniculata, and Pausinystalia trillesi. It is also found in Pseudocinchona africana and Rauwolfia canescens. 

Gaultheria procumbens Ilex paraguariensis Corynanthe yohimbe... 

The stem bark of P. yohimbe (= P. johimbe Corynanthe yohimbe), "yohimbe as it is known in Cameroon, Gabon and Congo is used traditionally as an aphrodisiac and stimulant to prevent sleep (41). The bark contains 1-6% of indole alkaloids, most of which are yohimbane-type alkaloids, the main one being yohimbine [7], which is structurally related to reserpine [8] (89). Yohimbine is a selective inhibitor of a-2- adrenergic receptors and, while at low dose it has hypertensive activity, at high dose it is hypotensive (vasodilation of peripheral vessels). It is the vasodilation of peripheral vessels, and especially vasodilation of the corpus cavemosum, which is the cause of the reputation of yohimbine as an aphrodisiac (90). Tests have shown, indeed, that increased... 

Yohimbine, an indolaUcylamine alkaloid, is chemically similar to reserpine. It is the principal alkaloid of the bark of the West African Corynanthe yohimbe tree and is also... 

Yohimbine Corynanthe yohimbe Stimulant purported aphrodisiac Hallucinations MAO Inhibition hypertension irritability gastrointestinal irritation. 

The bark of the tree Corynanthe yohimbe (Rubiaceae), indigenous to the Cameroons and the Congo Republic (formerly French Congo), has been used in the treatment of arteriosclerosis and is said to be an aphrodisiac. The princi-... 

Corynanthe yohimbe (Pausinystalia yohimbe Rubiaceae) is a evergreen tree native to the southern part of Africa and to Cameroon, Nigeria, and Zaire. Occasionally it is planted in tropical countries. Its bark coontains a total of 0.3%-1.5% alkaloids. The well known indole alkaloid yohimbine has been obtained as a major alkaloid from the bark. The bark has been used traditionally as an aphrodisiac by African natives. Yohimbine hydrochloride is used as an adrenergic blocker for humans. 

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