Core-shell nanogels

Fig. 11 Irradiation of micelles consisting of PI and PAA to obtain core-shell nanogels. (Reprinted from [28], copyright 2009, with permission of Elsevier)...

William, H. Blackburn, L. Lyon, A. Size-controlled synthesis of monodisperse core/shell nanogels. Colloid Polym. Sci. 2008, 286 (5), 563-569. 

Figure 4 Schematic illustrafion of the irradiation process of poly (isoprene-lEactylic acid) polymer micelles to obtain core-shell nanogels. Reprinted with permission from Narita, T. Terao, K. Dobashi, T. etal. Colloids Surf., 62004, 38,187-190. Copyright 2009 Elsevier.

Zhou and co-workers have prepared core-shell nanogels that combine bearing targeting, bearing imaging and temperature sensing in a single theranostic nanoparticle... 

Li, J., Yu, S., Yao, P., and Jiang, M. 2008. Lysozyme-dextran core-shell nanogels prepared via a green process. Langmuir 24 3486-3492. 

Tamura M, Ichinohe S, Tamura A, Ikeda Y, Nagasaki Y (2011) In vivo and in vitro characteristics of core-shell-type nanogel particles optimization of core cross-linking density and surface PEG density in PEGylated nanogels. Acta Biomaterialia. doi 10.1016/j. actbio.2011.05.027... 

Keywords Controlled/living radical polymerization Core-shell particle Dispersion polymerization Emulsion polymerization Grafting from Hybrid Miniemulsion polymerization Nanogel Nanoparticle... 

Wu, W. T. Zhou, T. Berliner, A. Banerjee, R Zhou, S. Q. Smart core-shell hybrid nanogels with Ag nanoparticle core for cancer cell imaging and gel shell for ph-regulated drug delivery. Chem. Mater. 2010, 22, 1966-1976. 

Wu, W., Shen, J., Baneijee, R, Zhou, S. (2010). Core-shell hybrid nanogels for integration of optical temperature-sensing, targeted tumorceUimaging, and combinedchemo-photothermal treatment. Biomaterials, 31(29), 7555-7566. 

Oishi, M. and Nagasaki, Y. (2007). Synthesis, characterization, and biomedical applications of core-shell-type stimuli-responsive nanogels - Nanogel composed of poly[2-(N,N-diethylamino)ethyl methacrylate] core and PEG tethered chains. Reactive and Functional Polymers, 67,1311-1329. 

Responsive nanogels have also been of great interest in recent studies because of their versatile properties (Ballauff and Lu, 2007). Most nanogels are composed of PNIPAM and its different copolymers, with a core-shell structure and with potential application in microfluidic devices, biosensing and molecular diagnosis (Kesselman et a/., 2012 Miyata et al. 

Figure 3.10 Schematic illustration of a multifunctional core-shell hybrid nanogel [178]. Reproduced with permission from W.T. Wu, T. Zhou, A. Berliner, R Banerjee, and S.Q. Zhou, Chemistry of Materials, 2010,22, 6, 1966. 2010, ACS...

FIGURE 16.1 Principal structural types of micro- and nanogels (a) Cross-linked networks, (b) networks associated with hydrophobic domains (e.g., cholesterol molecules), (c) core-shell structure of two different networks, (d) multilayer networks (microgel covered with two polyelectrolyte layers is shown), (e) composite solid core-soft shell networks containing metal, ceramic, or protein NPs, (f) composite raisin-in-pie type of microgel with metal NPs dispersed in the network. 

Sun, H., Yu, J., Gong, P., Xu, D., Hong, J., et al. 2006. Novel core-shell magnetic nanogels synthesized in an emulsion-free aqueous system under UV irradiation for potential targeted radiopharmaceutical applications. Int. J. Nanosci. 5 253-258. 

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