Core oligosaccharide structures

Cohen, R. E., Zhnag, W., and Ballou, C. E. (1982). Effects of mannoproteins in Saccharomyces cerevisiae core oligosaccharide structure. J. Biol. Chem., 257, 5730-5737. 

We will discuss below the main classes of core oligosaccharide structures (Holst, 2002, 2007 Holst and Molinaro, 2009) and in addition to these, the structure of the novel of core oligosaccharide published after the year 2007 and not yet included in the earlier reviews. 

Corsaro, M.M., Pieretti, G., Lindner, B., Lanzetta, R., ParriUi, E., Tutino, M.L., Parrilli, M. Highly phosphorylated core oligosaccharide structures from cold-adapted Psychromonas arctica, Chem Eur J 14 (2008) 9368-937. 

De Castro, C., Carannante, A., Lanzetta, R., Liparoti, V., Molinaro, A., Parrilli, M. Core oligosaccharide structure from the highly phytopathogenic Agrobacterium tumefaciens TT111 and conformational analysis of the putative rhamnan epitope. Glycobiology 16 (2006) 1272-1280. 

The completed lipid A-core oligosaccharide structure is transported across the plasma membrane by the ATP-dependent transporter MsbA. In vitro experiments with E. coli MsbA suggest that the ATPase recognizes only fully hexaacylated Kd02-lipid A, but the transporter appears to be slightly less selective in vivo [209]. Crystal structures have been reported for MsbA homologues from . coli and Vibrio cholera [210,211,212]. However, these structures... 

Chiew, Y.Y., Shepherd, M.G. Sullivan, P.A. (1980) Regulation of Chitin Synthesis During Germ-tube Formation in Candida albican. Archives of Microbiology, 125, 97-104 Cohen, R.E., Zhang, W-J. Ballou, C.E. (1982) Effects of Mannoprotein Mutations on Saccharomyces cerevisiae Core Oligosaccharide Structure , Journal of Biological Chemistry, 257, 5730-7... 

Muco-series Gaipi -3/4Gaipi -4Glcpi -1 Cer Fig. 15.4. Oligosaccharide structures of the core regions of the lacto-, globo-, muco- and... 

In a very elegant study, Droge and coworkers26 investigated the structures of the LPS from four Salmonella minnesota R-mutants designated mR595, mR3, mR7, and mR5. These mutants synthesize LPS that contains only lipid A and the inner core oligosaccharides,... 

Figure 14.2 Representative oligosaccharide structures found on mammalian glycoproteins and glycolipids. The complex oligosaccharides may be bi-, tri-, or tetra-antennary the branches may be more or less elongated with 1—>4 linked lactosamine units, and they may or may not be sialylated. The SLex, Lea, and Leb structures represent the different blood group determinants often present on lipids, and the elongated core 2 structure is a mucin-type glycosylation. Proteoglycans have a common core to which a variety of linear acidic polysaccharides are attached.

FIGURE 7-32 Bacterial lipopolysaccharides. (a) Schematic diagram of the lipopolysaccharide of the outer membrane of Salmonella ty-phimurium. Kdo is 3-deoxy-o-manno-octulosonic acid, previously called ketodeoxyoctonic acid Hep is L-glycero-D-mannoheptose AbeOAc is abequose (a 3,6-dideoxyhexose) acetylated on one of its hydroxyls. There are six fatty acids in the lipid A portion of the molecule. Different bacterial species have subtly different lipopolysaccharide structures, but they have in common a lipid region (lipid A), a core oligosaccharide, and an "O-specific" chain, which is the prin-... 

The transfer of the oligosaccharide to protein is followed in vivo by the excision of the D-glucosyl residues the nine D-mannosyl residues present in the transferred oligosaccharide probably remain in the inner core of the D-mannan. However, the possibility that some D-mannosyl residues could be almost simultaneously removed and added cannot be precluded.117,167 Finally, terminal, < -d-(1 - 3)-linked D-mannosyl groups are added to the trimmed, protein-bound oligosaccharide.118 The outer chain of the d-mannan is formed after the inner-core oligosaccharide has been transferred to protein and processed, apparently by direct transfer of D-mannosyl groups from GDP-D-mannose.168 The similarity of the structures of the outer chain... 

The Core. Core oligosaccharides are structurally less diverse than O-chains. The core oligosaccharide shown in Figure 1 is common to many or all Salmonella serotypes. Distinct core types have been... 

The structures of the core oligosaccharides have not been worked out in detail, but the analytical compositions (Table 111)... 

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