Lipopolysaccharides structures

FIGURE 7-32 Bacterial lipopolysaccharides. (a) Schematic diagram of the lipopolysaccharide of the outer membrane of Salmonella ty-phimurium. Kdo is 3-deoxy-o-manno-octulosonic acid, previously called ketodeoxyoctonic acid Hep is L-glycero-D-mannoheptose AbeOAc is abequose (a 3,6-dideoxyhexose) acetylated on one of its hydroxyls. There are six fatty acids in the lipid A portion of the molecule. Different bacterial species have subtly different lipopolysaccharide structures, but they have in common a lipid region (lipid A), a core oligosaccharide, and an "O-specific" chain, which is the prin-... 

N. K. Kochetkov, in L. Anderson and F. M. Unger (Eds.), Synthesis of O-antigenic polysaccharides. Pathways for the polymerization of oligosaccharide repeating units, Bacterial Lipopolysaccharides Structure, Synthesis and Biological Activities, ACS Symp. Ser., Vol. 231, Amer. Chem. Soc., New York, 1983, pp. 65-81. 

A. Gamian, E. Romanowska, A. Romanowska, C. Lugowski, J. Dabrowski, and K. Trauner, Citrobacter lipopolysaccharides Structure elucidation of the O-specific polysaccharide from strain PCM 1487 by mass spectrometry, one-dimensional and two-dimensional H NMR spectroscopy and methylation analysis, Eur. J. Biochem., 146 (1985) 641-647. 

Klein, G., Lindner, B., Brabetz, W., Brade, H., Raina, S. Escherichia coli K-12 suppressor-free mutants lacking early glycosyltransferases and late acyltransferases minimal lipopolysaccharide structure and induction of envelope stress response. J Biol Chem 284 (2009) 15369-15389. 

Vilches, S., Canals, R., Wilhelms, M., Salo, M.T., Knirel, Y.A., Vinogradov, E., Merino, S., Tomas, J.M. Mesophilic Aeromonas UDP-glucose pyrophosphorylase (GalU) mutants show two types of lipopolysaccharide structures and reduced virulence. Microbiology 153 (2007) 2393-2404. 

Kastowsky, M., Gutberlet, T., Bradaczek, H. Comparison of X-ray powder-diffraction data of various bacterial lipopolysaccharide structures with theoretical model conformations. Eur J Biochem 217 (1993) 771-779. 

De Castro, C., Molinaro, A., Lanzetta, R., Silipo, A., Parrilli, M. Lipopolysaccharide structures from Agrobacterium and Rhizobiaceae species. Carbohydr Res 343(12) (2008) 1924-1933. 

Mansson, M., Bauer, S.H., Hood, D.W., Richards, J.C., Moxon, E.R., Schweda, E.K. A new structural type for Haemophilus influenzae lipopolysaccharide. Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 486. Eur 1 Biochem 268 (2001) 2148-2159. 

Ulmer, A.J., Rietschel, E.T., Zahringer, U. Lipopolysaccharide Structure, bioactivity, receptors, and signal transduction. Trends Glycosci Glycotechnol 14 (2002) 53-68. 

Keywords Rhizobium Lipopolysaccharides Structure Biosynthesis Symbiosis Plant defense... 

Synthesis of Haemophilus influenzae and ducreyi Lipopolysaccharide Structures... 

Gerald s last campaign focused on the lipopolysaccharide structures produced by the human gastric pathogen Helicobacter pylori, the lipopolysaccharides of which... 

Fig. 5. Structure of KDOj-Lipid A. Lipid A is a disaccharide of glucosamine phosphate that is multiply acylated with both amide and ester linkages to fatty acids of the chain lengths indicated (12 and 14). As illustrated in Fig. 4, Lipid A is attached to KDOj that is then elongated with the remainder of lipopolysaccharide structure. Figure is courtesy of C.R.H. Raetz.

Rana FR, Macias EA, Suliany CM, Modzradowski MC, Blazyk J. Interactions between magainin 2 and SdtnoneUa lyphirmm um outer membranes Effect of lipopolysaccharide structure. Biochem 1991 30 5858-5866. 

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