CONTIN computer program

Because of the above-mentioned multimodal detection capability of the CONTIN computer program, photon correlation spectroscopy has been used effectively by Flamberg and Pecora (ref. 466) to detect translational and rotational motions of micelles in solution. The results obtained can best be explained by a micellar growth model. 

The analysis of the autocorrelation function data by the Coulter Model N4 is carried out by the Size Distribution Program (SDP), which gives the particle size distribution in the form of various output displays (see Section 10.4). The SDP analysis utilizes the computer program CONTIN developed by S.W. Provencher (ref. 467-470 see also Section 10.2). (This program has been tested on computer-generated data, monomodal polystyrene samples, and a vesicle system (ref. 466-468,471).) Since the SDP does not fit to any specific distribution type, it offers the ability to detect multimodal and very broad distributions. 

In practice the lifetime distributions are usually obtained using a computer program such as the MELT [21] or CONTIN [22, 23] programs. The reliablity of these programs for measurring the o-PS lifetime distribution in polymers was shown by Cao et al [24]. A detailed description of these methods of data analysis is presented in Chapter 4. The advantage of the continuous lifetime analysis is that one can obtain free volume hole distributions rather that the average values obtained in the finite analysis. 

IgiCr) I is inverse-Laplace transform. There are computer program packages available for the procedure. Among others, CONTIN has been most frequently used and implemented in commercial DLS measurement systems. The resnlt of the transformation is displayed in rC(r) on a logarithmic scale of T (Fig. 3.17b). The following eqnation explains why FG(r) is plotted, not just GIF) ... 

Until recently, most of the PAL data were analyzed in a finite-term lifetime approach. A computer program PATFIT, which represents annihilation lifetime distribution in a discrete manner, i.e. as a sum of several exponents, is en )loyed for this purpose. As an alternative, Gregory and Jean (10,11) proposed using a continuous lifetime analysis. In this approach the Laplace inversion program CONTIN, originally developed by Provencher (12) for analysis of fluorescence spectra, is used to obtain a continuous probability density function of annihilation lifetimes from PAL spectra. In this way one can obtain size distributions of FV in polymers. 

For both the subdistribution and the GEX fit methods a Marquardt algorithm for constrained non-linear regression was used to minimize the sum of squares error (.10). The FORTRAN program CONTIN was used for the constrained regularization method. All computations were performed on a Harris H-800 super mini computer. 

S.W. Provencher CONTIN program, EMBL Technical Reporty DA 05, European Biology Laboratory, Germany 1982 Comput. Phys. Commum., 27, 229 (1982)... 

Provencher, S.W. (1982) Contin A general purpose constrained regularization program for inverting noisy linear algebraic and integral equations. Comput. Phys. Com., 27,229-242. 

The evaluation of positron lifetime spectra is usually performed by commercial computer codes. POSITRONFIT and RESOLUTION programs (Kirkegaard et al. 1981) work on the basis of Eqs. (27.14) and (O 27.15) supplying the lifetimes and relative intensities of the assumed states as final results. Positronium lifetime distributions are obtained applying the CONTIN (Gregory and Zhu 1990) algorithm or the MELT (Shukla et al. 1993) code for lifetime spectra. 

Provencher, S. W., CONTIN A General Purpose Constrained Regularization Program for Inverting Noisy Linear Algebraic Integral Equations, Computer Phys. Comm., 1982, 27, 229-242. 

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