Considerations of Industrial Fine Chemical Synthesis

The oxidative dehydrogenation of alcohols represents key steps in the synthesis of aldehyde, ketone, ester, and acid intermediates employed within the fine chemical, pharmaceutical, and agrochemical sectors, with allylic aldehydes in particular high-value components used in the perfume and fiavoring industries [1]. For example, crotonaldehyde is an important agrochemical and a valuable precursor for the food preservative sorbic acid, while citronellyl acetate and cinnamaldehyde confer rose/fruity and cinnamon flavors and aromas, respectively. There is also considerable interest in the exploitation of biomass-derived feedstocks such as glycerol (a by-product of biodiesel synthesis from plant or... 

The construction of carbon-carbon bonds is one of the most important transformations in organic synthesis, and considerable research efforts have been directed towards the development of new methods in this area. Importantly, transformations of this type provide access to a wide variety of organic compounds that can be used as synthetic building blocks in the fine chemical and pharmaceutical industries, as well as key intermediates in the preparation of dmgs and functional materials. 

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