Conditional knock-ins

Another area where transgenic mice of greater sophistication are coming on line is conditional knock-ins and conditional knockouts. In conditional knock-in systems, expression of the transgene is under the control of a promoter that functions only when the animal is exposed to a pharmacologic... 

Knitgoods, dyeing, 0 171, 200, 201 Knitted fabrics, 24 619-620 Knitting, 11 178 cotton, 8 17-18 Knock, engine, 12 390-392 Knock-in mice, 12 462 Knock-out mice, 12 462 conditional, 12 467 Knock sensors, 12 394... 

Ignition by compression is similar to the conditions that generate knock in a spark-ignited automotive engine. Thus it would indeed appear that compression ignition and knock are chain-initiated explosions. Many have established... 

Figure 4.3 depicts three conditional strategies for point mutation knock-ins. All aim to satisfy a set of key requirements, namely (i) that the point-mutant allele be expressed from the... 

The original CFR test conditions appear in the second column of Table 7.2. These constitute the Research method and assign the fuel a Research octane number (RON). It was found that typical fuel susceptibility to knock in practical engines did not correlate sufficiently well with this test and one with rather more severe conditions - the Motor method, giving the Motor octane number (MON) - now also is used. These conditions are given in the third column. The inlet manifold temperature and speed have been increased, spark timing advanced, and a shrouded inlet valve fitted to... 

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