Compactor machine design, operating

Roller Compaction Technology for the Pharmaceutical Indnstry Table 5 Operating parameters and results of compactor machine design 1 when compacting poor flowing low density active drug substance ... 

Table 6 Operating Parameters and Results of Compactor Machine Design 1 When Compacting Poor Flowing Low-Density Active Drug Substance Blends...

The Fitzpatrick Co. roller compactor (Fig. 20) features two feed screws in series one horizontal and the second vertical. This system is designed to transfer powder bulk into a set of cantilevered rolls positioned in the horizontal mode one is fixed, the other floats. Operator interface allows for on-line monitoring and controlling feed screw speeds, roll pressure, and roll gap. Features such as on-line help and diagnostic functions, maintenance, and calibration screens are displayed. All functions are interfaced and adjustable by PLC for process control and report generating. The machines have vacuum deaeration and roll cooling capabilities. The sizing unit is separate from the compactor and is either a rotor bar or a hammer mill. 

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