Combines safety and

Ketoconazole. For treatment of systemic mycoses with amphotericin B or miconazole, the patient must be admitted to a hospital. This is not always possible, particularly in areas where systemic mycoses occur frequently, nor is it always desirable, because of the expense. For these reasons, it was desirable to find an antimycotic that combined safety and broad-spectmm activity with oral adraiinistration. Ketoconazole (10), which is orally active, met most of these requirements. This inhibitor of the ergosterol biosynthesis is an A/-substituted imidazole, that differs from its precursors by the presence of a dioxolane ring (6,7). Ketoconazole is rapidly absorbed in the digestive system after oral adrninistration. Sufficient gastric acid is required to dissolve the compound and for absorption. Therefore, medication that affects gastric acidity (for example, cimetidine and antacids) should not be combined with ketoconazole. 

To combine safety and comfort, some manufacturers have focused on incorporating ANSI 107 high-visibility standards into new apparel designs that allow for layering and flexibility. 

It was tried to align requirements for SILs (safety requirements) with related security requirements of appropriate level for products (components from CPS view point). This is based on the idea that a similar level of rigidness as defined e.g. in lEC 61508 and ISO 15408 should be applied to the SRLs on both sides (see Table 1). In case the risk and vulnerability analysis (combined safety and security analysis) provides evidence that different levels are required for both issues then the recommendations shall change. 

Uniform Approach of Risk Communication in Distributed IT Environments Combining Safety and Security Aspects... 

Abstract. We present patterns for expressing dependability requirements, such as confidentiality, integrity, availability, and reliability. The paper considers random faults as well as certain attacks and therefore supports a combined safety and security engineering. The patterns - attached to functional requirements - are part of a pattern system that can be used to identify missing requirements. The approach is illustrated on a cooperative adaptive cruise control system. 

Thus, the main objective of this book is to combine safety and reliability in the oil and gas industry into a single volume, eliminate the need to consult a number of different and diverse sources in obtaining desired information, and provide up-to-date information on the subject. The somces of most of the material presented are given in the reference section at the end of each chapter. These will be useful to readers if they desire to delve deeper into a specific area. This book contains a chapter on mathematical concepts and another chapter on safety and reliability basics considered useful to imder-stand the contents of subsequent chapters. Furthermore, another chapter is devoted to methods considered useful to perform safety and reliability analyses in the oil and gas industry. 

Only with the advent of DCS and PLC controllers did we have to pay attention to the question of combining safety and control in the same systems. There is a temptation nowadays to combine safety and control functions in the same equipment and it can be acceptable under certain conditions but it should be resisted wherever possible. It also depends on what is meant by combine . 

Combining safety and efficiency to dam inspection proj ects is a great challenge. The underwater robot developed integrates these two skills, with an immediate and achievable solution for monitoring the integrity of dams. 

A suitable maintenance strategy should be developed for equipment by considering the criticality and failure mode, and then applying a mixture of the forms of maintenance described above. In particular, the long-term cost of maintenance of an item of equipment should be estimated over the whole life of the project and combined with its capital cost to select both the type of equipment and form of maintenance which gives the best full lifecycle cost on a discounted basis), while of course meeting the technical, safety and environmental specifications. 

Waving Lotions. The reagent most frequently used for the reduction of hair is thioglycolic acid [68-11-1]. Although a variety of other mercaptans have been screened (51), none has been able to match the unique combination of efficacy, safety, and low cost that is a hallmark of thioglycolic acid. 

When illegal residues have been found in monitoring studies conducted by the FDA or USD A, the reason has often been that no U.S. tolerance had been requested for that particular pesticide in that specific crop. For example, an imported crop would be deemed to be adulterated and would be seized at the port of entry into the United States if found to contain a pesticide residue in the absence of a tolerance in that crop. This is so even if tolerances have been set for the same pesticide in several crops grown in the United States and the pesticide had been used to control a pest that does not exist in the United States. Furthermore, an international maximum residue level (MRL) might already have been estabUshed for that pesticide—crop combination under the Codex system of standards for food of importance in international trade. The U.S. GAO issued two reports on food safety and pesticides in 1991 (89,90). 

The primaiy purpose of materials selection is to provide the optimum equipment for a process application in terms of materials of construction, design, and corrosion-control measures. Optimum here means that which comprises the best combination of cost, life, safety, and reliability. 

When applying low temperature requirements, one should consider safety valve and flare headers to be subject to "shock chilling" if they can be exposed to cold liquids released into the system. This includes flare headers from blowdown drums into which cold liquids are discharged. Where laterals of different piping material are combined, the material of the lower-temperature header is continued for the rest of the combined line, and is also extended back into the other lines for 6 m. 

FIGURE >0.70 The capture of tracer gas released at five times the diameter of the exhaust inlet when the radius of the exhaust hood is 0. tS m, the radius of the exhaust hood inlet is 0.037 m, and the width of the exhaust jet is 8.0 mm. fej Suction alone with average inlet velocity of 12.7 m s. (b) Combined suction and Injection with the average inlet and exhaust velocities of 12 8 rn s and 7.7 m s . respectively. (Figures are courtesy of the Health and Safety Executive, Research Division. Sheffield. UK.)... 

The description of biological safety cabinets is also included in this section. Biological safety cabinets include those with combined supply and exhaust airflow, but also include other designs which are also described,... 

The vehicle also puts constraints on the choice of fuel. A combination of factors, such as the anticipated fuel and vehicle cost, both vehicular and well-to-wheels emissions and efficiency, perceived or real safety, and infrastructure will determine the choice of optimum fuel. 

An EU application for a combination product that contains previously authorised active substances must be supported by appropriate safety and efficacy data for the combination. However, there is no need to submit data on the safety and efficacy of the components individually. The combination product is considered a unique product distinct from the authorisations granted to the individual ingredients, and will thus have a separate exclusivity clock running from the date when the combination was authorised. 

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