Collagen, effect

Monomeric and fibrillar collagens effectively support platelet adhesion, whereas the native, triple-helical structure of collagen and the polymerisation of the monomeric collagen are required for collagen-induced platelet aggregation and secretion " . 

Wissink MJ, van Luyn M J, Beernink R, Dijk F, Root A A, Engbers GH, BeugeUng T, van Aken WG, Feijen J. Endothelial cell seeding on crossUnked collagen effects of crosslinking on endothelial cell proliferation and functional parameters. Thromb. Haemost. 84 325-331,2000. 

Components/ mechanism of action Human plasma, fibrinogen and thrombin, virally inactivated, hemostat, sealant. Autologous fibrinogen -t-platelet-rich plasma, hemostatic gel. Bovine collagen, bovine thrombin, plus autologous human plasma, hemostatic agent. Bovine collagen and bovine thrombin. Expands 20% which aids in hemostatic effect. 

Chapman, W., Sherman, R., Boyce, S., Malawer, M., Hill, A., Buncke, G., Block, J., Fung, J., Clavien, R, Lee, K., Lebovic, G., Wren, S., Diethrich, E. and Goldstein, R., A novel collagen-based composite offers effective hemostasis for multiple surgical indications Results of a randomized controlled trial. Surgery, 129, 445-450 (2001). 

UV-B causes sunburn, but UV-A damages collagen (connective tissue) and blood vessels, causing aging effects such as wrinkled skin. 

Tieszen, L.L. and Fagre, T. 1993 Effect of diet quality and composition on the isotopic composition of respiratory COj, bone collagen, bioapatite and soft tissues. In Lambert, J.B. and Grupe, G., eds.. Prehistoric Human Bone. Archaeology at the Molecular Level. Berlin, Springer-Verlag 121-155. 

Where CO2 in the free atmosphere has a 5 C value of-7%o, C3 and C4 plants are anticipated to have 5 C values of about -26.5%o and -12.5%o respectively (van der Merwe 1989) archaeological maize, however, typically averages -9.5%o(Schwarcz et al. 1985). The isotopic values of modern maize and C3 plant foods in Mesoamerica (Wright 1994 203-206), after correction for the Industrial Effect, average -9.6%o and -26.4%o respectively. Since herbivore collagen is typically enriched by +5%o relative to the diet (van der Merwe 1989), animals from this region with a pure C3 plant diet should... 

Figure 2.3. Carbon and nitrogen isotope values of human bone collagen at Maya sites in Belize. The value for the modem sample has been corrected for collagen-hair spacing and the Industrial Effect. Boxes represent isotopic means one standard deviation.

Fizet, M., Mariotti, A. and Bocherens, H. 1995 Effect of diet, physiology and climate on carbon and nitrogen stable isotopes of collagen in a Late Pleistocene anthropic palaeoecosystem Marillac, Charente, France. Journal of Archaeological Science 22 67-79. 

Schoeninger, M.J. 1985 Trophic level effects on and ratios in bone collagen and... 

In addition, our results suggest that removal of hpids improves both yield characteristics and elemental characteristics. Recent work by Liden et al. (1995) suggests that the methanol-chloroform method used here is more effective than other methods, such as treatment with NaOH solution, or the maintenance of an acidic environment and ultrafiltration of products during collagen extraction. It is speculated that the presence of hpids in archaeological bone samples may interfere with the acid hydrolysis of protein during... 

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