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Cognitive impairment in Parkinson’s disease

Perry EK, Curtis M, Dick DJ, et al Chohnergic correlates of cognitive impairment in Parkinson s disease comparisons with Alzheimer s disease. J Neurol Neurosurg Psychiatry 48 413-421, 1985... [Pg.718]

Aarsland D, Laake K, Larsen JP, et al Donepezil for cognitive impairment in Parkinson s disease a randomized, controlled study. J Neurol Neuro-surg Psychiatry 72 708-712, 2002... [Pg.213]

Leroi I, Brandt J, Reich SG, et al Randomized, placebo-controlled trial of donepezil in cognitive impairment in Parkinson s disease. Int J Geriatr Psychiatry 19 1-8, 2004... [Pg.216]

Cools R, Barker R, Sahakian BJ, Robbins TW (2001) Enhanced or impaired cognitive function in Parkinson s disease as a function of dopaminergic medication and task demands. Cerebral Cortex 77 1136-1143. [Pg.427]

Downes JJ, Sharp HM, Costall BM, et al Alternating fluency in Parkinson s disease. An evaluation of the attentional control theory of cognitive impairment. Brain 116 887-902, 1993... [Pg.627]

Fig. 7. Depiction of the hypothetical relationship between the locus of DA depletion in cortico-striatal loops , cognitive and motor performance and the effects of L-Dopa (see Swainson et al., 2000 Cools et al., 2001). Whereas some forms of cognitive performance are improved by L-Dopa in Parkinson s disease, reversal learning is impaired- possibly as a consequence of the ventral cortico-striatal loops being less severely depleted than the more dorsal loops , thus leading to effective over-dosing of this circuitry by L-Dopa. Adapted from Swainson et ah (2000). Fig. 7. Depiction of the hypothetical relationship between the locus of DA depletion in cortico-striatal loops , cognitive and motor performance and the effects of L-Dopa (see Swainson et al., 2000 Cools et al., 2001). Whereas some forms of cognitive performance are improved by L-Dopa in Parkinson s disease, reversal learning is impaired- possibly as a consequence of the ventral cortico-striatal loops being less severely depleted than the more dorsal loops , thus leading to effective over-dosing of this circuitry by L-Dopa. Adapted from Swainson et ah (2000).
Close relationships between the mean CBF and cognitive function have been observed [108], For example, in patients with Parkinson s disease and Alzheimer s disease, their cognitive function impairment is significantly negatively correlated with rCBF [109-111],... [Pg.950]

Use with caution in older patients with Parkinson s disease or parkinsonism, Psychosis, Renal impairment, Cognitive impairment... [Pg.793]

Growdon JH, Kieburtz K, McDermott MP, Panisset M, Friedman JH (1998) Levodopa improves motor function without impairing cognition in mild nondemented Parkinson s disease patients. Neurology 50 1327-1331. [Pg.429]

Beneath the cortex are several other important structures. The basal ganglia are structures involved in voluntary motor behaviour and consist of the caudate, putamen, globus pallidus and amygdale. The caudate and putamen together are known as the striatum. Degeneration of these stmctures in some diseases, for example Parkinson s disease, may cause cognitive and motor impairment (11, 17). [Pg.327]

Besides their use in Alzheimer s disease, cholinesterase inhibitors have been extended to treat other dementias and related illnesses, which may include vascular dementia, dementia with Lewy Bodies, dementia associated with Parkinson s, mild cognitive impairment, and mixed dementia. Research is particularly important in this area since it is not uncommon for Alzheimer s disease to be co-morbid with other types of dementia. Therefore, it is important to devote a section briefly discussing recent flndings and the use of... [Pg.45]


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See also in sourсe #XX -- [ Pg.475 ]




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Cognitive impairment

Impaired

Impairment

In Parkinson’s disease

Parkinson’s disease

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