Pill coatings

Drache, Drachen, m. dragon kite. Drachenblut, gummi, n. dragon s blood, dragieren, v.t. coat (pills or the like),... 

Figure 71. Sweetie Barrel. (Courtesy Western Cartridge Company.) The moist and mixed ingredients of bulk powder, tumbled in this apparatus, take on the form of grains. Similar equipment is used for sugar-coating pills and for applying a deterrent coating or a graphite glaze to grains of colloided smokeless powder.

Enteric-coated pills. See Enteric-coated doses. Enteric-coated tablets. See Enteric-coated doses. Epispastics Epispastics are local remedies, the application of which produce a serous discharge beneath the cuticle, forming a blister. Epispastics are also known as vesicatories. ... 

Parvules Small sugar-coated pills, of 0.06 g or less, sometimes incorrectly called granules, (also see Granules)P ... 

Pilula enterica Enteric-coated pills (see Pills). 

Some acid-sensitive drugs can be protected by the way they are formulated. For example, it is possible to coat pills with an acid-resistant polymer which protects the drug from the acids in the stomach. The polymer is designed to be removed under the slightly alkaline conditions of the large intestine. Unfortunately, absorption in the large intestine is not so efficient as the small intestine and so the applications are limited. 

Avicenna (Persia) Silver- and gold-coated pills... 

M. Labelonie (France) Sugar-coated pills (dragees)... 

US Patents 568 488 and 582 794, press for sugar-coating pills, pill machine... 

Note Pancreatin is destroyed in the stomach, hence should be given in salol -coated pills. 

Silver is used in the quartation of gold. Pharmacists coat pills with silver not merely to enhance their appearance but also to act as preservative, largely against moisture. 

Supplement vitamin Bi deficiency states, impaired absorption or increased requirements (pregnancy, lactation, alcoholism) Therapy beriberi, Wernicke s encephalopathy, neuritis, polyneuritis (alcoholic and toxic), neuralgia, myalgia, myocardia, disorders of the intermediate metabolism Thiamine chloride and hydrochloride, thiamine mononitrate, cocarboxylase, thiamine pyrophosphate Tablets, sugar-coated pills, dragees, ampules 50-300 mg 0.3-1.2 mg 1.0-1.4 mg... 

Tablets, ampules, sugar-coated pills, suppositories...

Hazardous Decomp. Prods. Heated to decomp., emits acrid smoke Uses Emulsifier, stabilizer, thickener in pharmaceuticals, adhesives, inks, textile printing, cosmetics, foods flotation depressant protective colloid mfg. of spray-dried flavors lithographic reagent lubricant emollient thickener, stabilizer for soft drinks, cake mixes, confectionery tablet binder/disintegrant/excipient gellant in medicated cough drops film-fonner for coat pills encapsulation for liposol. vitamins sus-... 

Diethylaminoethyl acrylate coating, PC film Vinylidene chloride copolymer coating, pigment Lipopur coating, pill... 

Eccobond OLF Eccobond W-20 film-former, clear wood coatings NeoCryl B-725 Photomer 3016-20H Photomer 3016-20R Photomer 3027 Photomer 3109 Photomer 3548 Photomer RM-370 Photomer RM-444 Photomer RM-445 film-former, cloth coatings CAP-482-0.5 CAP-482-20 film-former, coated pills Acacia... 

Like thiamine, riboflavin is also used for the fortification of certain foods, such as wheat flour and breakfast cereals. Because of its yellow-orange colour, it is also used as a colouring for certain foods, especially cereal products, ice creams and sugar-coated pills. Hydroxyl groups of ribitol can be easily esterified by carboxylic acids. For example, riboflavin-2, 3, 4 5 -tetrabutyrate has been used as an antioxidant. 

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