Classifier response continuous

The titration procedures described in the literature can be classified as continuous or incremental, depending on the mode of titrant addition. In the first case the titrant is continuously introduced in the reaction vessel at a programmed (not necessarily constant) rate during a run. The application of this method requires apparatus with quick response to temperature changes and can be used only to study fast reactions. Slow reactions (i.e., those with a reaction time longer than the equilibrium time of the reaction vessel) may be accurately studied by the... 

Another important feature of mathematical modeling techniques is the nature of the response data that they are capable of handling. Some methods are designed to work with data that are measured on a nominal or ordinal scale this means the results are divided into two or more classes that may bear some relation to one another. Male and female, dead and alive, and aromatic and nonaromatic, are all classifications (dichotomous in this case) based on a nominal scale. Toxic, slightly toxic, and non-toxic are classifications based on an ordinal scale since they can be written as toxic > slightly toxic > non-toxic. The rest of this section is divided into three parts methods that deal with classified responses, methods that handle continuous data, and artificial neural networks that can be used for both. 

FIGURE 28. Classifier with continuous or discrete response. 

Fisher s exact test should be used to compare two sets of discontinuous, quantal (all or none) data. Small sets of such data can be checked by contingency data tables, such as those of Finney et al. (1963). Larger sets, however, require computation. These include frequency data such as incidences of mortality or certain histopatho-logical findings, and so on. Thus, the data can be expressed as ratios. These data do not fit on a continuous scale of measurement but usually involve numbers of responses classified as either negative or positive that is, contingency table situation (Sokal and Rohlf, 1994). 

Besides the continuous effect models, drugs are often fitted to all-or-none models where the responses such as disappearance of arrhythmia in response to a drug dose cannot be graded the same results hold when we classify the response ending in cure or not, or presence or absence of a given side effect or effects. In such instances, EC50 is the median concentration for which half of the subject population is above the threshold and the slope of the curve becomes the variance of the threshold in that population. 

An attractive property of monolithic reactors is their flexibility of application in multiphase reactions. These can be classified according to operation in (semi)batch or continuous mode and as plug-flow or stirred-tank reactor or, according to the contacting mode, as co-, counter-, and crosscurrent. In view of the relatively high flow rates and fast responses in the monolith, transient operations also are among the possibilities. 

Many enzymes are classified as regulatory enzymes whose activities can be controlled continuously (from 0 to 100 percent) through combination with specific activators or inhibitors called modifiers. For example, if citrate, a major component of aerobic metabolism, is present in high concentration, it will activate the enzyme system responsible for the synthesis of fatty acids. Such regulatory enzymes are called allosteric enzymes. 

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