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Cisplatin Aminoglycosides

Hypomagnesemia has been associated with more than 50 drugs, especially those that are nephrotoxic, including cisplatin, aminoglycoside antibiotics, cyclosporine, and amphotericin B. Secondary hypocalcemia and hypokalemia may result with myasthenia and tetany (Swaminathan 2003). [Pg.155]

Aminoglycosides, amphotericin B, carboplatin, cisplatin, foscamet, and intravenous contrast dyes... [Pg.160]

Nephrotoxins (N) orototoxins (0) (eg., amphotericin B (N), cisplatin (N/0), cyclosporine (N), furosemide (0), NSAIDs (N), radio contrast (N), vancomycin (N) Additive adverse effects Monitor aminoglycoside SDC and renal function... [Pg.396]

Insulin overdose Miscellaneous Aminoglycosides Amphotericin B Cisplatin ... [Pg.905]

Hypomagnesemia is usually associated with disorders of the intestinal tract or kidneys. Drugs (e.g., aminoglycosides, amphotericin B, cyclosporine, diuretics, digitalis, cisplatin) or conditions that interfere with intestinal absorption or increase renal excretion of magnesium can cause hypomagnesemia. [Pg.906]

Examples of drugs that can give permanent damage to the inner ear or acoustic nerve are antibiotics (aminoglycosides) and chemotherapy (cisplatin). Other more commonly used drugs can give reversible ototoxity with vertigo. [Pg.74]

Primary renal cell culture has been utilized to study a number of nephrotoxic agents including mercuric chloride (Inamoto et al., 1976), cadmium (Cherian, 1982), lead (McLachlin et al., 1980), cisplatin (Tay et al., 1988), aminoglycoside antibiotics... [Pg.671]

Chatteijee et al., 1984 Sens et al., 1988), and cyclosporine (TrifiUis et al., 1984). Studies reported by Tay et al. (1988) in rabbit proximal tubule cultures with cisplatin revealed biochemical effects upon DNA synthetic activty that correlated with in vivo histochemical effects of this antitumor agent in animals. With respect to studies involving mercuric chloride and aminoglycoside antibiotics in primary renal cultures, light and electron microscopy revealed similar patterns of cellular pathology in vitro as compared to in vivo exposure in animals (Chatteijee et al., 1984 Aleo et al., 1987). [Pg.672]

Drugs that may interact with zalcitabine include antacids, chloramphenicol, cisplatin, dapsone, didanosine, disulfiram, ethionamide, glutethimide, gold, hydralazine, iodoquinol, isoniazid, metronidazole, nitrofurantoin, phenytoin, ribavirin, vincristine, cimetidine, metoclopramide, amphotericin, aminoglycosides, foscarnet, antiretroviral nucleoside analogs, pentamidine, and probenecid. [Pg.1865]

Drugs that may affect tacrolimus include nephrotoxic agents (aminoglycosides, amphotericin B, cisplatin, cyclosporine), antifungals, bromocriptine, calcium channel blockers, cimetidine, clarithromycin, danazol, diltiazem, erythromycin, methylprednisolone, metoclopramide, carbamazepine, phenobarbital, phenytoin, rifamycins, cisapride, chloramphenicol, metronidazole, nefazodone, omeprazole, protease inhibitors, macrolide antibiotics, fosphenytoin, and St. John s wort. [Pg.1938]

Uses Edema, HTN, CHF, h atic cirrhosis Action Loop diuretic -1- reabsorption of Na Cr in ascending loop of Henle distal tubule Dose 5-20 mg/d PO or IV 200 mg/d max Caution [B, ] Contra Sulfonylurea sensitivity Disp Tabs, inj SE Orthostatic -1- BP, HA, dizziness, photosens, electrolyte imbalance, blurred vision, renal impair Notes 20 mg torsemide = 40 mg furosemide Interactions t Risk of ototox W/ aminoglycosides, cisplatin t effects W/ thiazides t effects OF anticoagulants, antih5rpCTtensives, Li, salicylates X effects IT/barbiturates, carbamaz ine, cholestyramine, NSAIDs, phenytoin, phenobarbital, probenecid, dandehon EMS t Effects of anticoagulants monitor for S/Sxs tinnitus, monitor ECG for hypokalemia (flattened T waves) OD May cause HA, hypotension, hypovolemia, and hypokalemia give IV fluids symptomatic and supportive... [Pg.309]

The severity of aminoglycoside nephrotoxicity is additive with that of vancomycin, polymixin, gallium, furosemide, enflurane, cisplatin, and cephalosporins. Aminoglycoside nephrotoxicity is synergistic with that of amphotericin B and cyclosporine. [Pg.541]

Cephalosporins Aminoglycosides Antineoplastic agents Nitrosoureas Cisplatin and analogs Radiographic contrast agents Halogenated hydrocarbons Chlorotriiluoroethylene Hexafluropropene Hexachlorobutadinene T richloroethylene Chloroform Carbon tetrachloride Maleic acid Citrinin Metals Mercury Uranyl nitrate Cadmium Chromium... [Pg.707]

Increased risk of nephrotoxicity with cidofovir, aminoglycosides, carbopla-tin, cisplatin, clofarabine, efavirenz/emtricitabine/tenofovir, tacrolimus... [Pg.70]

Increased nephrotoxicity with cidofovir, aminoglycosides, carboplatin, cisplatin, clofarahine, efavirenz/emtricitahine/tenofovir, gallium, tenofovir... [Pg.72]

See other pages where Cisplatin Aminoglycosides is mentioned: [Pg.109]    [Pg.638]    [Pg.620]    [Pg.109]    [Pg.638]    [Pg.620]    [Pg.593]    [Pg.415]    [Pg.673]    [Pg.690]    [Pg.12]    [Pg.18]    [Pg.71]    [Pg.94]    [Pg.113]    [Pg.175]    [Pg.252]    [Pg.290]    [Pg.291]    [Pg.306]    [Pg.316]    [Pg.535]    [Pg.428]    [Pg.203]    [Pg.10]    [Pg.16]    [Pg.71]    [Pg.94]    [Pg.113]    [Pg.175]    [Pg.252]    [Pg.290]    [Pg.291]    [Pg.306]    [Pg.316]    [Pg.407]   
See also in sourсe #XX -- [ Pg.620 ]



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Cisplatin

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Cisplatin with aminoglycosides

Cisplatine

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