Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Chromosomal translocation analysis

Brewen, G.J., R.J. Preston, and N. Gengozian. Analysis of x-ray induced chromosomal translocations in human and marmoset stem cells. Nature 253 468-470, 1975. [Pg.256]

Southern Blot Hybridization Analysis for the Detection of Chromosomal Translocations... [Pg.1464]

SBH analysis is an excellent method for the detection of chromosomal translocations. A sequence-specific probe to the gene of interest is used for SBH analysis as described for the antigen-receptor genes. Detection of a pattern in which bands of different sizes than are seen in the germline con-... [Pg.1464]

The polymerase chain reaction is a methodology that is very well suited for the analysis of chromosomal translocations, particularly when the translocation breakpoints are clustered and the sequences flanking the translocation breakpoints are well characterized. [Pg.1464]

Weiss LM, Warnke RA, Sklar J, Cleary ML. Molecular analysis of the t(14 18) chromosomal translocation in malignant lymphomas. N Engl J Med 1987 317 1185-9. [Pg.1481]

PFG can vastly simplify genetic analysis as demonstrated in its application to analysis of yeast chromosomal translocations. [Pg.175]

Figure 5. Yeast Chromosomal Trsmslocation Analysis. Ethidium bromide-stained gel. The first lane was loaded with size markers eus in Figure 4. Other lanes were alternately loaded with wild-type yeast (no translocations) and a strain containing a translocation between chromosomes 3 and 12. Experimental conditions were as in Figure 3, using 1.5% low endoosmosis agarose gel. The arrow indicates the position of the wild-type chromosome and the absence of the translocated chromosome. Figure 5. Yeast Chromosomal Trsmslocation Analysis. Ethidium bromide-stained gel. The first lane was loaded with size markers eus in Figure 4. Other lanes were alternately loaded with wild-type yeast (no translocations) and a strain containing a translocation between chromosomes 3 and 12. Experimental conditions were as in Figure 3, using 1.5% low endoosmosis agarose gel. The arrow indicates the position of the wild-type chromosome and the absence of the translocated chromosome.
During mitosis, aU the DNA is highly condensed to allow separation of the sister chromatids. This is the only time in the ceE cycle when the chromosome structure is visible. Chromosome abnormalities may be assessed on mitotic chromosomes by karyotype analysis (metaphase chromosomes) and by banding techniques (prophase or prometaphase), which identify aneu-ploidy, translocations, deletions, inversions, and duplications. [Pg.12]

Cytogenetic analysis of patients with chronic myelogenous leukemia (CML) reveals an unusual translocation between chromosomes 9 and22 termed the Philadelphia chromosome."... [Pg.212]

See other pages where Chromosomal translocation analysis is mentioned: [Pg.40]    [Pg.12]    [Pg.129]    [Pg.148]    [Pg.11]    [Pg.786]    [Pg.1464]    [Pg.1477]    [Pg.2488]    [Pg.107]    [Pg.122]    [Pg.431]    [Pg.574]    [Pg.1375]    [Pg.2249]    [Pg.688]    [Pg.597]    [Pg.31]    [Pg.44]    [Pg.57]    [Pg.306]    [Pg.84]    [Pg.150]    [Pg.150]    [Pg.850]    [Pg.456]    [Pg.1691]    [Pg.147]    [Pg.612]    [Pg.207]    [Pg.181]    [Pg.640]    [Pg.641]    [Pg.641]   


SEARCH



Chromosomal analysis

Chromosomal translocation

Chromosome translocation

Translocated

© 2024 chempedia.info