Chromosomal regions

QTLs were also detected in tomato introgression lines (domestic tomatoes with single, defined chromosome regions selected from the progeny of a cross with a wild, non-pigmented variety) that correspond to candidate loci for which genes and mutants have been previously characterized. Detected QTLs included the r locus Psy), the Del locus (LcyE), and the B locus. Similar to the tissue-specific expression of maize Yl, the B locus codes a fruit-specific lycopene cyclase associated with higher levels of P-carotene. ... 

Segura A, PV Biinz, DA D Argenio, LN Ornston (1999) Genetic analysis of a chromosomal region containing van A and van B, genes required for conversion of either ferulate or vanillate to protocatechuate in Acinetobacter. J Bacterial 181 3494-3504. 

Budarf M. L., Konkle B. A., Ludlow L. B., et al. Identification of a patient with Bemard-Souli-er syndrome and a deletion in the DiGeorge/velo-cardiofacial chromosomal region in 22q 11.2. Hum Mol Genet 1995 4, 763-6. 

Zavattari P, Deidda E, Whalen M et al. Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations demography, chromosome recombination frequency and selection. Hum Mol Genet 2000 9 2947-2957. 

FIGURE 45-2 Missense mutations in the a-synuclein gene and multiplication of the chromosomal region containing the a-synuclein gene cause autosomal-dominantly inherited forms of Parkinson s disease and dementia with Lewy bodies. The a-synuclein gene is shown schematically in green. 

The immune system is a very complex system with many redundant control systems. One hint of this complexity is that idiopathic lupus has a high genetic component, and there are 48 chromosomal regions that have been linked to the risk of idiopathic lupus yet, the child of a person with lupus only has a 5% chance of developing lupus [107],... 

While some histone variants can become deposited during DNA replication, certain variants also are assembled into chromatin in a replication-independent manner (reviewed in Jin et al. 2005). This allows the incorporation of histone variant into chromosomal regions with high levels of histone turnover. Histone variants can distinguish the affected nucleosomes from their canonical counterparts and are likely to have important function in the specialization of chromatin domains and their epigenetic maintenance. 

Inactivation of specific chromosomes or chromosomal regions during development One X chromosome in each cell of a woman is inactivated by condensation to heterochromatin (Barr bodies)... 

In studying a large number of families with a small deletion in a specific chromosome region, it is noted that the disease phenotype is distinctly different when the deletion is inherited from the mother as opposed to the father. What is the most likely explanation ... 

Protein-coding genes within a chromosomal region can be identified by finding ... 

---