Chromatoid

In an ideal stain, the cytoplasm of cysts and trophozoites is blue-green tinged with purple. Entamoeba coli cyst cytoplasm is often more purple than that of other species. Nuclear chromatin, chromatoid bodies, erythrocytes, and bacteria stain red or purplish red. Other ingested particles such as yeasts often stain green. Parasite eggs and larvae usually stain red. Inflammatory cells and tissue cells stain in a fashion similar to that of protozoa. Color reactions may vary from the above. 

An investigation of the effect of dithiocarbamates on the chromosomes of bone marrow cells showed that ziram and, particularly, TMTD causes chromosomal aberrations. The effect of ethylenebisdithiocarbamates is considerably milder. All of the aberrations produced by these compounds were of the chromatoid type (Kurinnyi and Kondratenko, 1972). 

Confirming the results of experiments on plants, several assays performed in vitro on mammalian cells have shown that arsenicals display evident clastogenic properties and can efficiently induce micronuclei, and slightly sister chromatoid exchanges SCEs in various mammalian and human cell systems (Basu etal. 2001). As expected, trivalent compounds are more efficient in that... 

Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M. TDRD5 is required for retrotiansposons silencing chromatoid body assembly and spermiogenesis in mice. J Cell BioL 2011 192 781-95. 

Benzene and its metabolites have long been known to cause chromosomal aberrations of various types of cell cultures of exposed humans. (To be discussed in Chapter 20.6 in fliis book entitled as Benzene Exposure and Sister Chromatoid Changes.) While it is true fliat genetic changes have been described and frequently effect chromosomes 5 and 7, and ofli-ers, there is no scientific evidence that these are required for the diagnosis of benzene exposure related cancers. Specifically, many cases of patients who have been exposed to... 

Entamoeba invadens In vivo. Chromatoid bodies Helical. 600 t wide Repeat distance 1290 % EN reconstruction at 107-129 X resolution a... 

Lake, J.A., and Slayter, H.S., 1972, Three-dimensional structure of the chromatoid body helix of Entamoeba invadens, J. Mol. Biol., 66 271. 

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