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Christmas factor

Antihemophilic factor B, Christmas factor, plasma thromboplastin component (PTC)... [Pg.600]

IX Christmas factor Intrinsic Activated IX directly activates X (intrinsic system)... [Pg.330]

IX Christmas Factor MW 47kD single-chain glycoprotein absence - Hemophilia B. [Pg.132]

Factor IX (Christmas factor) is next in the intrinsic mechanism cascade. It can be activated either by XIa or by Vila of the tissue factor pathway. The absence of a functional factor IX leads to the inherited X-linked bleeding disorder hemophilia B which affects 1 in 30,000 males. The condition can be mild or very serious551552 and may be caused by a variety of mutations or by incorrect splicing of the messenger RNA for the 416-residue factor IX. The level of factor IX in blood increases with age, almost doubling by old age.552a... [Pg.633]

Hageman factor (XII), antihemophilic globulin (VIII), Christmas factor (IX), plasma thromboplastin antecedent (XI), calcium (IV), and platelet phospholipids... [Pg.42]

The intrinsic and extrinsic pathways cross over at several points. Hageman factor, activated by the intrinsic pathway, can switch on proconvertin of the extrinsic pathway. Convertin can then feed back into the intrinsic pathway to help activated PTA activate Christmas factor. Thrombin itself can trigger both branches of the clotting cascade by activating antihemophilic factor, which is required to help activated Christmas factor in the conversion of Stuart factor to its active form, and also by activating proconvertin. ... [Pg.85]

Yang again Christmas factor from Stuart factor. For a period, both bind to proaccelerin. [Pg.93]

Yin Antihemophilic factor from proaccelerin. Quickly adapts to interact with Christmas factor. [Pg.93]

Figure 5.3. Intrinsic and extrinsic blood clotting cascades. Factor I, fibrinogen Factor II, prothrombin (vitamin K-dependent) Factor III, thromboplastin Factor V, proac-celerin Factor VII, proconvertin (vitamin K-dependent) Factor VIII, antihemophilic factor Factor IX, Christmas factor (vitamin K-dependent) Factor X, Stnart factor (vitamin K-dependent) Factor XI, plasma thromboplastin Factor XII, Hageman factor Factor XIII, fibrin-stabilizing factor and Factor XIV, protein C (vitamin K-dependent). What was at one time called Factor IV is calcinm no factor has been assigned nnmber VI. Figure 5.3. Intrinsic and extrinsic blood clotting cascades. Factor I, fibrinogen Factor II, prothrombin (vitamin K-dependent) Factor III, thromboplastin Factor V, proac-celerin Factor VII, proconvertin (vitamin K-dependent) Factor VIII, antihemophilic factor Factor IX, Christmas factor (vitamin K-dependent) Factor X, Stnart factor (vitamin K-dependent) Factor XI, plasma thromboplastin Factor XII, Hageman factor Factor XIII, fibrin-stabilizing factor and Factor XIV, protein C (vitamin K-dependent). What was at one time called Factor IV is calcinm no factor has been assigned nnmber VI.
IX Pla. nia ihmmboplastin component . Christmas factor, platelet cofnetor II. uutoprothioinbin II. untihcinophilic factor B... [Pg.664]

Chorionic growth-hormone prolactin. 845 Christmas factor, recombinant. 185 Chromatography affinity, in receptor isolation. 28 in combinatorial clicmisiry. 51 high-pcfformancc liquid. 51. 833 ion exchange. 8.34 paper. 834... [Pg.964]

Genetically, determined clotting diseases include classical haemophilia, which is due to lack of factor VIII, and there is another form of haemophilia due to deficiency of factor IX (Christmas factor). These are treated by giving fresh donor blood or plasma, preparations of factor VIII or factor IX, or increasingly as one of the recombinant versions which are becoming available. [Pg.138]

Christmas factor deficiency Hereditary retinal degenerative diseases... [Pg.535]

Christmas factor, antihemophilic factor B IX Hemophilia B, Christmas disease 20-30 per 1,000,000 5 0.1 Liver 12-24 ICFH, ICFI, lEDM, HXA, IPFX FA9 HUMAN... [Pg.843]

L2. Limdblad, R. L., and Davie, E. W., The activation of antihemophilic factor (factor VIII) by activated Christmas factor (activated factor IX). Biochemistry 3, 1720-1725 (1964). [Pg.221]

L12. Lindquist, P. A., Fujikawa, K., and Davie, E. W., Activation of bovine Factor IX (Christmas Factor) by Factor XI. (activated plasma thromboplastin antecedent) and a protease from Russell s viper venon. J. Biol. Chem. 253, 1902-1909 (1978). [Pg.164]

See other pages where Christmas factor is mentioned: [Pg.207]    [Pg.170]    [Pg.291]    [Pg.426]    [Pg.112]    [Pg.755]    [Pg.170]    [Pg.911]    [Pg.207]    [Pg.84]    [Pg.89]    [Pg.90]    [Pg.94]    [Pg.95]    [Pg.204]    [Pg.186]    [Pg.104]    [Pg.845]    [Pg.185]    [Pg.76]    [Pg.118]    [Pg.1788]    [Pg.1834]   
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See also in sourсe #XX -- [ Pg.330 ]

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See also in sourсe #XX -- [ Pg.632 ]

See also in sourсe #XX -- [ Pg.843 ]

See also in sourсe #XX -- [ Pg.632 ]

See also in sourсe #XX -- [ Pg.632 ]

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See also in sourсe #XX -- [ Pg.388 , Pg.389 ]

See also in sourсe #XX -- [ Pg.66 ]



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