Plasma thromboplastin antecedent

XI Plasma thromboplastin antecedent Intrinsic Activated form (XIa) serves to activate IX... 

Tissue factor/thromboplastin xi Plasma thromboplastin antecedent (PTA) 3.4.27.27... 

Hageman factor (XII), antihemophilic globulin (VIII), Christmas factor (IX), plasma thromboplastin antecedent (XI), calcium (IV), and platelet phospholipids... 

Hageman Factor (Factor XII) and Plasma Thromboplastin Antecedent (Factor XI), /. Lab. Clin. Med. (1972) 80, 704. 

L12. Lindquist, P. A., Fujikawa, K., and Davie, E. W., Activation of bovine Factor IX (Christmas Factor) by Factor XI. (activated plasma thromboplastin antecedent) and a protease from Russell s viper venon. J. Biol. Chem. 253, 1902-1909 (1978). 

Eujikawa, K., Legaz, M.E., Kato, H., Davie, E.W. 1974. The mechanism of activation of bovine factor IX (Ghristmas factor) by bovine factor XIa (activated plasma thromboplastin antecedent). Biochemistry 13, 4508-4516. 

Plasma thromboplastin antecedent Hageman factor Fibrin stabilizing factor... 

XI Plasma thromboplastin antecedent M, 124000 (bovine), 160000 (human). Glycoprotein composed of 2 similar or identical polypeptides joined by disulfide bond(s). Activates IX.IXa is inhibited by antithrombin III, trypsin inhibitors, a,-trypsin inhibitor and Cl inhibitor. 

Deficiencies in other factors, such as the plasma thromboplastin antecedent, the accelerator globulin, and the serum prothrombin conversion factor have all been described. The deficiencies lead to various forms of hemophilia. The severity of degree of bleeding episodes is much less marked than in classical hemophilia. These deficiencies are usually congenital, transmitted by sex-linked dominant or recessive or by autosomal dominant genes. The manifestations of these deficiencies are usually referred to as hemophilioid states c, d, a, and b, respectively. The major characteristics of these various types of congenital hemophilioid states are summarized in Table 7-4. 

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