Choline chloride Carbachol

Choline theophyllinate Choline chloride Carbachol Choline salicylate Choline dihydrogen citrate Ferrocholinate Chromic acid... 

C2H5CIO 107-07-3) see Acetylcholine chloride Carbachol Choline chloride Etofylline Homofenazine Metronidazole Oxypendyl Tofenacin Troxerutin ethylenediamine... 

C3H< N 75-50-3) see Acetylcholine chloride Betaine hydrate Bethanechol chloride Carbachol Carnitine Cetrimonium bromide Choline chloride Choline hydroxide Decamethonium bromide Hexcarbacholine bromide Miltefosine Prolonium iodide... 

Carbachol. Choline chloride carbamate is nonspecific in its action on muscarinic receptor. subtypes. The pharmaco-... 

Bethanechol Chloride, USP. Bethanechol. jS-mcthyl-choline chloride carbamate. (2-hydroxypropyl)trimethylam-monium chloride carbamate, carbamylmelhylcholinc chloride (Urecholinc), is nonspecific in its action on muscarinic receptor. subtypes but appears to be more effective at eliciting pharmacological action of M> receptors. It has pharmacological properties similar to those of methacholinc. Both are esters of nicthylcholine and have feeble nicotinic activity. Bethanechol is inactivated more slowly by AChE in vivo than is mcthacholine. It is a carbamyl ester and is expected to have stability in aqueous solutions similar to that of carbachol. 

Carbachol may be prepared by reacting choline chloride with phosgene in chloroform solution followed by treatment of the product with ammonium hydroxide. 

Carbaminoylcholine chloride, a synthetic derivative of choline, is not destroyed by cholinesterase. Carbachol is a rather long-acting and powerful miotic, which can cause various ocular side effects, i.e. headaches, ocular and periorbital pain, twitching of the eyelids, ciliary congestion and spasm of accommodation. Rapid formation of cataracts was observed in 3 patients. Carbachol must be formulated with a wetting agent to increase penetration. 

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