Cholagogic effect

The diuretic and cholagog effect of Ononis arvensis motivated the development of a new two-dimensional paper chromatographic and TLC method for the measurement of onion in its roots and aerial parts. Samples were dried, ground and extracted with methanol (70 per cent, w/v) for 2 h. The supernatant was diluted and used for TLC separation on a cellulose stationary phase. The first eluent was 3 per cent formic acid, and the second was n-butanol-acetic acid-water (4 1 5, v/v) for both TLC and paper chromatography. Spots were scraped off, extracted with methanol and the absorption was measued at 260 nm. It was found that the average ononin content in roots and aerial parts was 0.153 0.0278 (per cent) and 0.498 0.045 (per cent), respectively. Because of the simplicity, the method was... 

Z0344 Yamahara, J., K. Miki, T. Chisaka, et al. Cholagogic effect of ginger and its active constituents. J Ethnopharmacol 1985 13(2) 217-225. 

Because of its antispasmodic, carminative, choleretic, and cholagogic effects it is traditionally used for treating gastrointestinal disorders and also in mucusdissolving and broncholytic preparations. In pharmaceuticals it is a compound in antipruritic, antiseptic, and cooling preparations [40]. 

Yamahara J, Kobayashi M, Miki K, Kozuka M et al. 1985 Cholagogic and antiulcer effect of Saussureae radix and its active components. Chem Pharm Bull 33 1285-1288... 

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