Chlordimeform structure

Figure 1. Structures of octopamine, norepinephrine, the pesticide/pestistat chlordimeform (CDM), and related compounds.

This new compound was the prototype for several series. From this original structure were developed amitraz (85), chlormethiuron (86), cymiazole (87) and clenpyrin (88), all of which have been used to control OP-resistant strains of B. microplus. Chlordimeform (84) was later withdrawn from sale and amitraz (85) became the market leader. There is... 

The formamidine acaricides and insecticides, chlordimeform and ami-traz, are lethal to all life stages of acarines, but their activity to insects is considerably more restricted (1). Using the southern cattle tick, Boophilus microplus, and the twospotted spider mite, Tetranychus urticae, the structural requirements of formamidines for lethality have been elucidated ( -5), an< t ie structure (lethal moiety) for maximum activity is shown in Figure 1. Briefly, the ring must contain two substituents, and they must be located at positions two and four maximum activity was observed when position... 

While chlordimeform itself did not block uptake at this concentration, DCDM and, particularly, DDCDM did cause inhibition. It is worth noting that the unmethylated formamidine, DDCDM, most closely approximates the structure of OA in this series. These... 

Other miscellaneous classes Besides the major classes of carcinogenic pesticides summarized above, specific structural features may account for carcinogenicity of some pesticides. For example, the amidine pesticide, chlordimeform, is carcinogenic most probably... 

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