Chitosan organ distribution

Figure 10.10 (a) In vivo near-infrared (NIR) fluorescence images of nude mice after intravenous injection of pluronic-based nanocarriers, (b) Ex vivo NIR fluorescence image of major organs B, brain S, spleen L, Aver H, heart Lm, lung K, kidney), (c) Quantification of the nanocarriers accumulated in the sacrificed brain, (d) Quantification of the nanocarriers distributed in the brain and major organs excised from the mice at 48 h post injection. ( = 3, p<0.01 Bare-NC, Chito-NC, RVG-Bare-NC vs. RVG-Chito-NC). Chito, chitosan RVG, rabies virus glycoprotein NC, nanocarrier. 

Clays (such as montmorillonite, laponite etc.) are usually employed as reinforcing filler to improve thermal stability as well as the stiffness and tensile strength of polymeric materials. Montmorillonite and organically modified montmoriUonites -the latter showing an increased interfacial interaction between clay and polymer macromolecules - were incorporated into different polymeric materials such as PU [54], PCL [55], and chitosan/PVA [56], The incorporated clays were well distributed, exfoliated and oriented along the fiber axis. It was reported that, during the... 

It has also long been acknowledged that the presence of a small amount of salt leads to a more uniform distribution of the short chain components among the polyelectrolyte with the longer chains, and thus thermodynamic equilibrium [23], More recently it has also been demonstrated that temperature annealing can lead to more organized liquid crystalline structures of DNA—lipid systems [55] and single-molecule structures of xanthan—chitosan systems [56] (see below). 

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