Lipid systems

Phase transitions have been characterized in a number of different pure and mixed lipid systems. Table 9.1 shows a comparison of the transition temperatures observed for several different phosphatidylcholines with different fatty acyl chain compositions. General characteristics of bilayer phase transitions include the following ... 

HUANG s w and frankel e n (1997) Antioxidant activity of green tea in different lipid systems , JAgric Food Chem, 45, 3033-8. 

The phase transition of bilayer lipids is related to the highly ordered arrangement of the lipids inside the vesicle. In the ordered gel state below a characteristic temperature, the lipid hydrocarbon chains are in an all-trans configuration. When the temperature is increased, an endothermic phase transition occurs, during which there is a trans-gauche rotational isomerization along the chains which results in a lateral expansion and decrease in thickness of the bilayer. This so-called gel to liquid-crystalline transition has been demonstrated in many different lipid systems and the relationship of the transition to molecular structure and environmental conditions has been studied extensively. 

PAMPA 50+ MODEL LIPID SYSTEMS DEMONSTRATED WITH 32 STRUCTURALLY UNRELATED DRUG MOLECULES... 

Garti N, Sato K (eds) (2001) Crystallization Process in Fats and Lipid Systems. Marcel Dekker, Inc, New York... 

---