Chironex fleckeri

Medusozoa Cubozoa Cubomedusae Chirodropidae (Chironex fleckeri) Chiropsalmus quadrigatus)... 

Coelenterate (cnidarian) toxins are found in venomous jellyfish and sea anemones. They produce not only severe pain, but also contact dermatitis that may include hemolysis and scarification. Some jellyfish envenomations are fatal, to include stings by both large (Chironex fleckeri) and small (Carukia barnesi) Australian box jellyfish (Watters, 2006a). Anaphylaxis may occur with species that have less toxic venoms. Prevention from envenomation by those who enter the marine environment is therefore clinically important. 

B. The Australian box jellyfish Chironex fleckeri, AKA sea wasp ) is the most venomous marine animal and is responsible for numerous fatalities. It should not be confused with the Hawaiian box jellyfish Carybdea alata). 

B. Specific drugs and antidotes. Box jellyfish (Chironex fleckeri) antivenin from Australia terminates acute pain and cardiovascular symptoms, prevents tissue effects, and may be located by a regional poison control center (in the United States, [800] 222-1222) for use in severe cases. Local marine biologists can help identify Indigenous species for planning of specific therapy. 

O Reilly GM et al Prospective study of Jellyfish stings from tropical Australia, including the trtajor box jeiiyfish Chironex fleckeri. Med J Aust 2001 175(11-12) 652-655. [PMID 11837877] (Review of causes and ciinical courses of 40 pafients with jel ish stings-mostly C fleckeri-presenting to a hospitai in tropical Australia. None of the cases was severe and none required antivenom.)... 

The box jellyfish, Chironex fleckeri, has been responsible for numerous fatalities or severe injuries. Endean and Rifkin 260) found that toxic material released from the isolated nematocysts of C.fleckeri rapidly produced marked systemic effects in mice when injected intravenously, but no such effects after subcutaneous or intraperitoneal injec-... 

Endean, R., and J. Rifkin Envenomation Involving Nematocysts of the Box Jellyfish Chironex fleckeri. Toxicon Suppl. 3, 115 (1983). 

Olson, C.E., E.E. Pockl, G.J. Calton, and J.W. Burnett Immunochromato-graphic Purification of a Nematocyst Toxin from the Cnidarian Chironex fleckeri (Sea Wasp). Toxicon 22, 733 (1984). 

Endean, R. and Henderson, L. (1974) Some aspects of the biological activity of cmde nematocyst toxin from Chironex fleckeri, in Bioactive Compound from the Sea (eds H.J. Humm and C.E. Lane), Marcel Dekker Inc., New York, pp. 1—13. 

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