China pharmaceutical

Cinmetacin North China Pharmaceutical Group Corp. (NCPC) ... 

The major manufacturers include DSM, BASF, and four Chinese producers, viz. Northeast Pharmaceutical, North China Pharmaceutical, Shijiazhong Pharmaceutical, and Jiangshan Pharmaceutical. The current world supply of ascorbic acid is more than 80 thousand metric tons per year with annual revenues in excess of US 700 million. 

Beining Chen graduated from China Pharmaceutical University with a B.Sc., in 1984 and an M.Sc. in 1987, both in medicinal chemistry. She obtained a Ph.D in organic chemistry in 1991 from University of Glasgow under the supervision of Professor Gordon Kirby. After spending three years working for Professor Sir Jack Baldwin at University of Oxford and seven years of employment by Cranfield, she joined Department of Chemistry at University of Sheffield as a lecturer in medicinal chemistry in 2003. 

Jun Li, School of Chemical Biology and Pharmaceutical Studies, Capital Medical University of Medical Sciences, Beijing, China, Pharmaceutical Bioassay... 

Plant material. The plant of /. denticulata f pirmatipartita Kitag.was collected in Dabie Mountains at Luotian county, Hubei province, China, in October 1992. /. sonchifolia Hance. was purchased from Nanjing Company of Traditional Chinese Medicine, in February 1991. Voucher specimen is deposited in the Herbarium of the Department of Pharmacognosy, China Pharmaceutical University. 

Zhen-Tao Warig Department of Pharmacognosy China Pharmaceutical University No 1 Shennong Rd. Nangjing, 210038 P. R. China... 

Zheng, P.Q., Formulation of Chinese Medicines, China Pharmaceutical Technology Press, Beijing, China, 1998. 

Gao XD, Wu WT (1994) Effect of Danggui (Angelica sinensis) and ferulic acid on immune system. Third International Congress on Ethnopharmacology and its Contemporary Utilization. China Pharmaceutical Association, Beijing, B-58... 

Liu JL, Zhang LH, Qian YK (1994) Immune tumor-inhibition of Lycium barbarum on S 180-bearing mice. 3rd International Congress on Ethno-pharmacology and Its Contemporary Utilization. China Pharmaceutical Association, Beijing, D-34... 

Vitamin C (L-ascorbic acid, l-AA), is an essential nutrient for humans and some animal species [9] (Figure 10.1). l-AA is a cofactor of at least eight enzymatic reactions, which are crucial for collagen synthesis. Deficiency in L-AA could cause the most severe symptoms of scurvy in humans [10]. L-AA can also act as an antioxidant [11], and is required for a range of essential metabolic reactions in all animals and plants [9,12]. It is produced internally by almost all organisms with the exception of some species of birds and fish [12, 13]. All species that do not synthesize ascorbate require it in their diet. L-AA is also widely used as a food additive to prevent the oxidation of other nutrients or some food dyes [14]. The global vitamin C production is currently estimated at about 11000 tons annually. The main producers include DSM (Scotland) and other four producers in China (Northeast Pharmaceutical Co. Ltd., North China Pharmaceutical Co. Ltd.,... 

Tu, G. S. 1988. Pharmacopoeia of the People s Republic of China (English Translation of 1985 Pharmacopeia of the People s Republic of China). China Pharmaceutical Books Co., Hong Kong, China. 

Visiting Scientist on sabbatical leave from the China Pharmaceutical University, Nanjing, China... 

State Key Laboratory of Natural Medicines, China Pharmaceutical University,... 

The environment for intellectual property protection is still a concern in China. Pharmaceutical companies ve been alarmed by the 2004 legal decision to overturn the Chinese patent for Pfizer s Viagra (sildenafil citrate). This was followed by a case where GlaxoSmithKline stepped back from defending its patent in China for rosiglitazone, the active ingredient of its anti-diabetes drug Avandia. 

---