Chicago add ,

Solvent of arystallization, 42 Solvents distilling off, 21 for recrystallization, 35 Spiral gas washing bottle, 62 Spot test reagents, 396 SS acid (Chicago add), see 1-Amino-8-naphthol 2,4-disulfonic add... 

In a 3-I. beaker a paste is made from 82 g. (0.21 mole) of 88 per cent technical Chicago add (i-amino-8-naphthol-2,4-disul-fonic add) (Note 3) and 500 cc. of water, and solution effected by the addition of 8 g. (0.2 mole) of sodium hydroxide in 30 cc. of water, testing with litmus toward the end and leaving the reaction still add (Note 4). The solution is cooled to 18° by the addition of ice, and just before the coupling 35 g. (0.33 mole) of anhydrous sodium carbonate is added. 

With dgorous mechanical agitation the diazoniiam salt solution is run into the Chicago add solution rather rapidly. The blue dye which separates at first, gradually dissolves on further stirring. After one-half hour the solution is tested for alkalinity (Note s) 4nd for completeness of coupling (Notes 6 and 7). 

Throughout the coupling an alkaline reaction should be maintained and sodium carbonate added if the alkalinity falls. If the mixture gives tests for both diazonium compoimd and Chicago acid, insufficient time has elapsed for complete coupling. A little more Chicago add should be added (in alkaline solution) if a deficiency is shown. 

The test for completeness of coupling involves testing for excess diazonium salt (a) and for excess Chicago add (6) ... 

The red impiuity is another dye produced by coupling of the diazonium salt with an oxidation-product which is present in the technical Chicago add. It is easier to free the blue dye of this red impurity by resalting than to purify the Chicago acid. However, in the case of Trypan blue (tolidine coupled with two moles of H add) the red mpurity cannot be removed by salting. 

Article Sex Case Queries Add to Belgian Scandal by Ray Mosely Chicago... 

After Werner von Bolton of Charlottenburg succeeded in 1903 in refining the metal, it soon acquired a limited use as filaments (34). It was found, moreover, that surgical and dental instruments made from it can be sterilized by heating or by immersion in adds without damage to the tantalum. Since the price was almost prohibitive, however, Dr. Balke set to work in Chicago to make the metal on a commercial scale. 

R. Marc Dahlgren, Ivory Technical Center. The Procter 4 Gamble Company, Cincinnati, OH, http //www.pg.com/. Soaps Joseph P. Daniszewski, E. /. Dh Pont de Nemours 4 Co., Inc.. Wilmington, DE, http //www.duponi.coni/ag/. Information Retrieval Rathin Datta, Consultant, Chicago, IL Hydroxycarboxylic Adds Darwin D. Davis, E. I. Dn Pont de Nemours 4 Co.. Inc.. Victoria, TX. 

Figure 36- i Purine and pyrimidine bases and the formation of complementary base pairs. Dos/ied //nes indicate the formation of hydrogen bonds. (In RNA, thymine is replaced by uracil, which differs from thymine only in its lack of the methyl group.) (Modified from Piper, M.A., Unger, E.R. Nucleic Add Probes A Primer for Pathologists. Chicago, ASG Press, 1989.)... 

Figure 37-19 Melting curve of double-helical nucleic acid. (Modified with permission from Piper MA, Unger ER Nucleic Add Probes A Primer for Potho/og/sts. Chicago, ASCP Press, 1989.)...

Brown, Herbert C. (1912-2004). An English-born chemist who was the recipient of the Nobel Prize for chemistry with Wittig in 1979. Via his work in organic synthesis, Brown discovered new routes to add substituents to olefins selectively. His early education was irregular and disjointed as a result of family circumstances and the economic depression of the 1930s. He eventually received his Ph.D. from the University of Chicago. The reduction of carbonyl compounds with diborane was the topic of his thesis. The bulk of his career has been spent at Purdue University. 

One reason interest in H202 as a therapeutic agent waned is because animal experiments were often negative or contradictory. Dr. Lorencz, from the University of Chicago, for instance, found that intravenous peroxide therapy didn t add oxygen to the system in dogs, rats, and roosters. That s why you have to be very careful in projecting animal results to humans. 

Typical of Chicago restaurants, Amitabul has a good selection of beers and wines to add cheer to your meal. What s not so typical is the smoke-free environment. 

James Dewey Watson (1928- ) was born in Chicago, Illinois, and enrolled in the University of Chicago at age 15. He received his Ph.D. in 1950 at the University of Indiana and then worked at Cambridge University in England from 1951 to 1953, where he and Francis Crick deduced the structure of DNA. After more than 20 years as professor at Harvard University, he moved in 1976 to the Laboratory of Quantitative Biology at Cold Spring Harbor, Long Island, New York. He shared the 1960 Nobel Prize in medicine for his work on nucleic adds., ... 

Another famous appHcation of mechanistic chemistry was contributed by Morris Kharasch (1895-1957) at the University of Chicago. It was well known since the mid-19th century that addition reactions of HX (HCl, H-OH, etc) to unsymmetrical alkenes occur in a manner that places hydrogen on the olefinic carbon attached to more hydrogen atoms than the other olefinic carbon (Markovnikov s rule). However, when HX is hydrogen bromide (HBr), addition is typically anti-Markovnikov. Kharasch found that traces of peroxides (commonly present on glassware surfaces) initiate a free radical chain reaction for HBr (not for other HX). Careful removal of peroxides Ifom glassware prior to reaction removes the potential free radical mechanism and HBr adds in a normal Markovnikov mode (intermediacy of carbocation, rather than Ifee radical, intermediates). 

H. W. Davenport, The ABC of Add-Base Chemistry, 14th ed.. University of Chicago Press,... 

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