Chemical reactivity functional groups

The R groups of the non-polar, alipathic amino acids (Gly, Ala, Val, Leu, lie and Pro) are devoid of chemically reactive functional groups. These R groups are noteworthy in that, when present in a polypeptide s backbone, they tend to interact with each other non-covalently (via hydrophobic interactions). These interactions have a significant stabilizing influence on protein conformation. 

Certain structural features, including whether it contains functional groups such as aldehydes, ketones, nitriles, or isocyanates, often define a class of chemicals. If information on the mechanism of action of a hazardous property of a chemical is not known, or if variances in the chemical s hazard through structural modification cannot be determined, then the assumption that certain chemically reactive functional groups can react similarly with the body or in the environment is often a good starting point in the process of evaluating the safety of solvents. 

Titrations are relatively simple and rapid. They provide information concerning chemically reactive functional groups that would be difficult to obtain by other techniques. 

The attractive features of this approach are the ability to rapidly introduce several different diversity elements within the template as well as the ability to link the template to a variety of components. Additionally, any of the groups attached to the template may include a chemically reactive functional group that can be further elaborated. 

Having physiochemical properties that improve probability of success in drug development by addressing issues of absorption and bioavailability including the filtering out of chemically reactive functional groups and peptides, compliance with ROF, etc. ... 

Another method used to improve the strength of a bond is to introduce the chemical reactive functional groups directly on the surface of the material. For example, the bonding of Teflon or polyethylene can be improved by introducing OH groups onto the plastic surface by sparking moist air next to the surface to be joined. This is best done by means of a Tesla coil or a Corona discharge. 

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