Chemical CRAMPS

A case report of acute arsine poisoning in which a 27-y-old man was exposed to arsine during chemical manufacturing was reported by Pinto (1976). The subject was exposed to arsine as a result of arsine production via a reaction between a galvanized bucket and an arsenic-containing sulfuric acid solution. The exposure (duration not specified) produced toxic effects characterized by abdominal cramping, thoracic discomfort, and hematuria. Over the next week, the patient s hematocrit declined from 42.5 to 27.1 and hemoglobin dropped from 14.1 to 9.5 g/dL even with medical intervention (blood transfusions and mannitol diuresis). Nine hours after exposure, blood arsenic was 159 g/dL and urinary arsenic was 1862 ug/L. 

Nocturnal habits and dark living environments have led to the evolution of olfaction as a major method of communication in many rodents. Although the dark and cramped habitats of many rodents complicate the study of their behavior, they can mostly be bred in large numbers under controlled conditions at modest cost and they are therefore ideal animals to use in the study of certain semiochemical phenomena. A considerable body of information on the chemical cues regulating the social and reproductive systems of these animals has thus been gathered over the last two to three decades. 

AZP, the most-recently characterized marine seafood poisoning, is associated with eating shellfish contaminated with azaspiracids. The first human intoxications attributed to AZP occurred in the Netherlands, and the symptoms included those similar to DSP (i.e., nausea, vomiting, severe diarrhea, and stomach cramps). However, although chemical analyses did not identify significant levels of the diarrhetic shellfish poisons, they identified a new class of toxins (James et ah, 2003a). 

Symptoms of exposure May cause pain and slight eye irritation. Excessive exposure may cause headache, dizziness, nausea, muscle twitching, incoordination, abdominal cramps, diarrhea, sweating, blurred vision, pinpoint pupils, salivation, tearing, tightness in chest, excessive urination, convulsions (Turf Ornamental Chemicals Reference, 1991). 

Figure 7.12 shows the FI traces taken from the 2D plots at 7.3, 3.0 and Oppm. The aromatic resonances at 7.3 ppm (bottom trace in Figure 7.12) are very well resolved, while the aliphatic and vinyl protons of cod ligand (middle trace) are broad and hidden in the baseline. The upper trace, taken at Oppm, represents the pure signal of methyl proton bonded to silicon residue. Despite the fact that 2D CRAMPS experiment enabled us roughly to assign the position of cod protons, the exact chemical shifts of other hydrogens remain equivocal. 

Alee Vera (Aloe barbadensis) Uses Topically for bums, skin irritation, sunburn, wounds internally used for constipation, amenorrhea, asthma, colds Actions Multiple chemical components aloinosides inhibit H20 electrolyte reabsorption irritates colon which T peristalsis propulsion wound healing d/t i production of thromboxane A2, inhibiting bradykinin, histamine Available forms Apply gel topically 3-5/d PRN caps 100-200 mg PO hs Contra Do not use if PRG, lactating, or children <12 y Notes/SE Abd cramping, D, edema, hematuria, hypokalemia, muscle weakness, dermatitis Interactions w/ internal use T K+ loss W/ BB, corticosteroids, diuretics, licorice T effects OF antiarrhythmics, corticosteroids, digoxin, diuretics, hyperglycemias, jimsonweed EMS Assess for dehydration, electrolyte imbalance (hypokalemia), abd distress w/ internal use stimulates uterine contractions may cause spontaneous abortion... 

Cramp on. C. A. Faber. G. Jons. R. Leaver. J. P. SchcDc. S. In The Modem Inorganic Chemicals Industry Thompson. R-, Ed. Cbctiicjl Society Special PnbScalion No. Jl Chcrrical Society London, 1977 p 244... 

In general, multiple pulse techniques sufficiently average the dipolar interactions, compress the chemical shift scale, but they do not affect heteronuclear dipolar interactions and the chemical shift anisotropy. A combination of both multiple pulse techniques and magic angle spinning, so-called CRAMPS (Combined Rotational And Multiple Pulse Spectroscopy) is found to yield satisfactory results in the solid state H NMR of solids 186). The limitations of all these techniques, from the analytical point of view, arises from the relatively small chemical shift range (about 10 ppm) as compared with some other frequently studied nuclei. However, high resolution H NMR of solids is useful in studies of molecular dynamics. 

However, if the patient has also been abusing other inhalants, the detoxification period could conceivably take up to 40 days, depending on the chemicals involved. Withdrawal symptoms in inhalant abusers may include nausea, vomiting, muscle pain and cramping, chills and sweats, irritability, tremors, headaches, and hallucinations. Depending on the severity of the symptoms and the patient s physical condition, the controlled environment of a residential setting may be preferred for the detox period. 

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