Solutions check

Of course it is not possible to make all the solution matrices identical, because we cannot know all that is in the sample solutions. However, if the sample extract or digest solutions are in 1 M HC1, for example, then all the standard solutions, blank solutions and check solutions should also be in 1 M HC1. One advantage of increasing the sensitivity of an... 

Throughout the text we use dimensional analysis in solving problems. In this approach, units are multiplied together, divided into each other, or canceled. Using dimensional analysis helps ensure that solutions to problems yield the proper units. Moreover, it provides a systematic way of solving many numerical problems and of checking solutions for possible errors. 

Using a DeVilbiss Model 40 Inhalation Medication Nebulizer or equivalent, the test conductor shall spray the threshold check solution into the enclosure. The nozzle is directed away from the nose and mouth ofthe person. This nebulizershall be clearly marked to distinguish it from the fit test solution nebulizer. 

The Threshold Check Solution is prepared by adding 13.5 milligrams of Bitrex to 100 ml of 5% salt (NaCl) solution in distilled water. 

Figure 2 Consistency of moisture determination of commercially available check solution by Karl Fischer coulometric assay.

After preparation and packaging, enemas have to be checked for appearance, labelling and packaging. The final volume or the final weight must also be checked. Solutions must be clear and visually free from particles. For a suspension enema the resuspendability must be evaluated, which may be done following the method for oral suspensions, see Sect. 32.7.2. For other quality requirements see Table 32.2. 

In order to obtain optimum performance, care must be exercised in the selection and control of both materials and procedures. Attention must be given to such details as checking solutions and chemicals used in the... 

The threshold check solution is prepared by dissolving 0.83 gram of sodium saccharin LISP in 100 ml of warm water. It can be prepared by putting 1 ml of the fit test solution (see (b)(5) below) in 100 ml of distilled water. 

Calibration checks Using calibration curves, analyses are performed on calibrated instruments. Any calibration has a limit lifetime and thus should be checked regularly, either as part of each batch or on a time schedule, such as daily. A calibration check solution should be prepared from material that is completely independent of tirat used to prepare the calibration standards. Replicates A replicate is a subsample, also occasionally referred to as an aliquot. Performing at least three replicates allows for simple statistics to be calculated (mean, s, %RSD). Often, time constraints within the laboratory dictate which samples are done in replicate. Replicates are frequently, but not always, analyzed at different times. °... 

ICS A 1 nterference check solution A Checks for freedom from interference at blank level in the presence of interfering species After initial calibration No specific requirements <3 X contract required quantitation limit value (CRQL)... 

Standards for Calibration and Quality Control Check Solutions—Use of chemicals of at least 99 % purity is highly recommended when preparing calibration and quality control check samples. If reagents of high purity are not available, an accurate assay of the reagent must be performed using a properly calibrated GC or other techniques (for example, water determination). 

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