Chain-link models

In Bowman and Narayandas (2004), we present a chain-link model of customer profitability using these data. The results from this study may... 

Figure 1. The model structure of plant RG-11 [1, 13] with four oligoglycosidic side-chains linked to the homogalacturonan backbone.

Virtually all published chain-link or cascading models linking vendor resource inputs with customer-level profits share roots in Heskett, et al. s (1994) Service-Profit Chain (SPC). Examples include its derivatives (e.g. Kamakura, Mittal, de Rose, Mazzon, 2002 Love-man, 1998 Soteriou Zenios, 1999), the return-on-quality (ROQ) framework (Rust, Zahorik, Keiningham, 1995), and the general satisfaction-profit chain (Anderson Mittal, 2000). Further, with one exception (Bowman Narayandas, 2004), all are developed in a consumer setting. 

Following the identification of KDO as a constituent of LPS, studies by Osborn and her group ( 5) have revealed that, in LPS, KDO (or the KDO region ) is located at the reducing end of the polysaccharide chain, linking the core segment to lipid A. Later, the application of differential color reactions based on thiobarbituric acid (TBA tests) (6, 7) has led to the view that KDO is present, in LPS from Salmonella or E. coli, in the form of a branched trisaccharide (Fig. 1). In this model, a branchpoint KDO residue (KDO I), ketosidically-linked to the second glucosaminyl residue of lipid A, is substituted in position 4 or 5 by a... 

One such model is the ideal freely jointed segments chain (Fig. 6.14). In this model the polymer is considered to consist of a chain of n links. We call each chain link a subunit . Each subunit has a length l. This parameter / can correspond to the length of a monomer but it can also be shorter or longer. The angle between adjacent chain links is taken to be arbitrary. The chain forms a random coil. To characterize the size and volume of such a coil we use the mean square of the end-to-end distance R2. The square-root of this value — we call it the size of a polymer chain — is given by... 

Nevertheless, improving or even innovating SCM design and operations is a reliable way to boost ROIC and therefore market value, as supply chains link nearly all parts of a company s business system. When Dell developed its radically new supply chain model, it was really thinking out of the box , and probably no one would have believed it would soon become the reference in (and outside) its industry, and one of the biggest and most valuable players in its sector. Similarly, other industries have indicated ways that the chemical industry can take in the near future. 

Fig. 9. Proximity relationships for residues in Cl relative to 316 in H8. Example of R1 distance mapping in rhodopsin. For each distance measurement, only two R1 side chains were in the protein, one fixed at the reference site 316, and the other at a site in the sequence 55-75. The R1 side chains were modeled based on crystal structure data with energy minimization subject to the experimentally determined distance constraint (shown). In each case, the measured distances in solution were in good agreement with those expected from the rhodopsin crystal structure. Substituted cysteine residues 65 and 68 most rapidly formed disulfide cross-links with the reference cysteine at 316 in H8. This is indicated by the dark bars connecting the potential disulfide partners.

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