Cell adhesion activation

Kubota K, Furuse M, Sasaki H, Sonoda N, Fujita K, Nagafuchi A, and Tsukita S [1999] Ca2" " -independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions. Curr Biol 9 1035-1038... 

Chen Q, Kinch MS, Lin TH et al. Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J of Biol Chem 1994 269 26602. 

Salminen, T. A., Smith, D. J., Jalkanen, S., and Johnson, M. S., 1998, Shiictural model of the catalytic domain of an enzyme with cell adhesion activity hiunan vascular adhesion proteinol (HVAP-1) D4 domain is an amine oxidase. Protein Engineering, ll 1195nl204. 

Additionally, saikosaponin D isolated from the roots of B. falcatum exhibited a potent anti-cell adhesive activity and a strong hemolytic action [53, 54]. It is suggested that the mechanism for anti-cell adhesive activity of this compound may resemble the mechanisms for its hemolytic action [ 55]. Saikosaponin D has been shown to inhibit the cell growth and DNA synthesis of several human cell lines, including human hepatoma cells [56]... 

Due to the established cell adhesive activity of fibronectin, it is not surprising that fibronectin also is involved in the control of cell motility and cell shape. Via the phagokinetic track method, it has been shown that the motility of cells increases with added fibronectin (31) and we have recently shown that heparin related molecules augment the action of fibronectin in this system (31). In addition to the stimulatory activity of fibronectin on the motility of several cell types in vitro, fibronectin has also been shown to be involved in the migration of neural crest cells in ovo (37). 

Arg-Gly-Asp-Ser-immobilized membrane cell adhesion activity, 72-74/ coupling, 72 synthesis, 68,72... 

Elloumi I, Kobayashi R, Funabashi H, Mie M, Kobatake E (2006) Construction of epidermal growth factor fusion protein with cell adhesive activity. Biomaterials... 

Maeda, T., Titani, K., Sekiguchi, K. (1994). Cell-adhesive activity and receptor-binding specificity of the laminin-derived YIGSR sequence grafted onto staphylococcal protein A. Journal of Biochemistry, 115(2), 182-189. 

Fig. 4 Tethering of short bioadhesive peptides onto nonfouling surfaces supports cell-adhesive activities. A Schematic diagram showing specific integrin binding to bioadhesive RGD motif. B RGD immobilization onto nonfouling support promotes cell adhesion and spreading...

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