Catheter systems connector

Plasmid-mediated resistance to silver salts is of particular importance in the hospital environment, because silver nitrate and silver sulphadiazine may be used topically for preventing infections in severe burns. It may have increased relevance in the future arising from the use of silver-coated connectors in catheter systems. Silver reduction is not a primary resistance mechanism as sensitive and resistant cells can equally convert Ag+ to metallic silver. Plasmid-mediated resistance to silver salts is, in fact, difficult to demonstrate, but where it has been shown to occur, decreased accumulation rather than silver reduction is believed to be the mechanism involved. 

Peritonitis is a leading cause of morbidity in PD patients, which often leads to loss of the catheter and subsequent change to HD as the treatment modality. However, recent advances with connectors used during instillation and drainage of dialysate and delivery systems have dramatically decreased the incidence of peritonitis. Peritonitis can be caused by chemical irritation or microorganisms. 

Polyurethane Good chemical resistance, toughness, good processabihty Catheters, tubing, LV. connectors, drug delivery systems... 

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