Casey, Charles

Charles P. Casey, University of Wisconsin, Madison Mary L. Mandich, Lucent-Alcatel, Murray Hill, New Jersey... 

Mark Cardillo, Camille Dreyfus Foundation, New York William Carroll, OxyChem, Dallas, Texas Charles Casey, University of Wisconsin, Madison Alexander Chuang, Case Western Reserve University, Cleveland, Ohio... 

Charles P. Casey (NAS) is Homer B. Adkins Professor of Chemistry at the University of Wisconsin, Madison. Dr. Casey s research lies at the interface between organometallic chemistry and homogeneous catalysis, and his group studies the mechanisms of homogeneously catalyzed reactions. He received his B.S. degree from St. Louis University and his Ph.D. from the Massachusetts Institute of Technology. 

The experimental and developmental work upon which this report is based was conducted by E. G. Bassett, R. L. Charles, P. R. Casey, R. R. Barton, and G. B. Borglum of the Enzymology Research Laboratory, and by W. W. Windish and L. A. Zawodniak of the Takamine Plant, with the assistance of numerous other individuals. 

CHARLES P. CASEY and STEPHEN M. NEUMANN Department of Chemistry, University of Wisconsin, Madison, WI 53706... 

Initially, the most obvious mechanism for olefin metathesis was a land of molecular square dance in which two different olefin molecules join to form a cyclobutane ring and then change partners to form two new olefin molecules. While this thermal reaction is Woodward-Hoffmann forbidden, transition metals were initially perceived to allow violations of these rules. However, no cyclobutanes were detected in olefin metathesis reactions, nor did cyclobutanes produce olefins when placed into metathesis reaction mixtures. The breakthrough came in 1971 when Yves Chauvin (1930- ), at the French Petroleum Institute, made the concepmal link between the Phillips Petroleum reaction discovered in 1964 and metallocarbenes isolated in the same year by Ernest Otto Fischer (see chapter 7). Other important discoveries were made by Michael F. Lappert (1928- ) at Sussex, Charles P. Casey (1942- ) at Wisconsin, and especially Thomas J. Katz (1936- ) at Columbia. The mechanism involves formation of a metallocyclobutane (see the accompanying figure), from reaction of a metallocarbene ( M=CR 2 ) with an olefin (R2C=CR2), that splits into a new olefin (R 2C=CR2) and a new metallocarbene ( M=CR2 ). 

Nicholas Cozzarelli said he did not think that librarians really want to support all of the activities of the American Chemical Society or the American Society of Biochemistry and Molecular Biology, but rather they want to buy that society s journal. He thinks the system has brought about some excesses and listed the salaries of ACS officers as an illustration. Charles Casey spoke for himself (as the 2004 ACS president) and said that he was lobbying for more openness and internally trying to get some moderation in ACS salaries. 

Charles P. Casey received his early education in St. Louis, Missouri (B.S. in chemistry, St. Louis University, 1963). His graduate research with George M. Whitesides at the Massachusetts Institute for Technology (MIT) was on organocopper compounds. After receiving his Ph.D. in 1967, he spent several months at Harvard University as a National Science Foundation (NSF) fellow in the laboratories of Paul D. Bartlett. In 1968, he joined the faculty at the University of Wisconsin-Madison where he is now Homer B. Adkins Professor of Chemistry and Steenbock Professor in the Physical Sciences. He was department chair at Wisconsin from 1998 to 2001. He was President of the American Chemical Society (ACS) in 2004. 

Hydroformylation of Olefins (Written with Prof. Charles P. Casey)... 

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