Case study drinking water ingestion

Information on the association of arsenic with skin cancer has primarily involved nonoc-cupational populations exposed to contaminated drinking water. Ingestion of arsenic has also been associated with lung, liver, bladder, and kidney cancers. Dose-response data for these cancers are available from epidemiological studies of a Taiwanese population exposed for 45 years to high levels of arsenic in the drinking water and involving more than 7000 cases of arsenical disease. For water arsenic... 

Hepatic Effects. Hepatic failure was reported in the case of an accidental ingestion of trichloroethylene that led to an acute overdose (Kleinfeld and Tabershaw 1954). In other case studies, blood analyses revealed no hepatic injury in a man who drank several tablespoons of trichloroethylene (Todd 1954) or in women who drank about 20 mL (Morreale 1976) or an unknown quantity (Perbellini et al. 1991). Self-reported liver problems were not increased among persons in the trichloroethylene subregistry who were exposed to trichloroethylene in their drinking water (ATSDR 1994 Burg et al. 1995). 

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