Cascara sagrada fluid extract

The Food and Drug Administration (FDA) has mled that the stimulant laxatives aloe (including aloe extract and aloe flower extract) and cascara sagrada (including casanthranol, cascara fluidextract aromatic, cascara sagrada bark, cascara sagrada extract, and cascara sagrada fluid extract) in over-the-counter formulations are not safe and effective or are misbranded (9). 

Cascara sagrada is available in tablets, capsules, liquids (fluid extracts), and syrups. Fluid extracts are more reliable than the solid dosage forms. Aromatic cascara fluid extract is less bitter and less active than cascara sagrada fluid extract because of the use of magnesium oxide in its preparation (Curry, 1986). Cascara tea is available, but has an extremely bitter taste (Tyler, 1994). 

Aromatic fluid extract, Cascara Sagrada fluid extract)... 

Oil is used mainly as a flavoring agent in pharmaceutical preparations (e.g., Aromatic Cascara Sagrada Fluid extract) fruits are used as aromatic and carminative and in preparations to prevent griping (martindale). 

Cascara sagrada is used as a cathartic. It is most useful when prepared as a fluid extract, and tends to be a mild laxative causing Htfle discomfort. However, on prolonged use it may result in characteristic melanotic pigmentation of the rectal mucosa. The bitter taste can be lessened, owing to neutralization of the acid constituents, if the ground substance is moistened and mixed with magnesium or calcium hydroxide. This treatment may lessen the potency of the preparation. 

OTC Aromatic Cascara Fluid extract, Cascara Sagrada, Cascara Aromatic Chemical Class Anthraquinone derivative... 

Cascara sagrada, an anthraquinone glycoside mixture (325 mg p.o. h.s., 1 mL fluid extract daily or 5 mL aromatic fluid extract daily), is used in acute constipation and preparation for bowel or rectal examination. 

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