Cardio-vascular system

One more example of acute polychlorpinen poisoning occurred in the Ukraine around 1969-70, when 27 women aged 26-49 were sent out to sow collective farm fields three days after the fields had been treated with polychlorpinen. A warm rain washed the pesticide from the soil, and the pesticide evaporated intensively. All the women showed symptoms of acute poisoning 20-40 minutes later eight lost consciousness, and nine had fits. The poisoned women spent from 3-25 days in the regional hospital, after which they all went to the VNIIGINTOKS clinic with disruptions of the neural and cardio-vascular systems, as well as of the digestive tract over the next 9-13 months [43]. 

It is found in many cellular complexes, such as the CNS, the peripheral nervous system and the cardio vascular system, but it also appears in blood cells. 

The relative efficaqr of entrapment of contrast materials into different liposomes as well as advantages and disadvantages of various liposome types were analyzed by Tilcock (157). Liposomal contrast agents have been used for experimental diagnostic imaging of liver, spleen, brain, cardio-vascular system, tumors, inflammations and infections (156, 158). 

Documented effects Effects on the cardio-vascular system and blood coagulability is equal to that of Lagochilus inebrians Bunge (Abdurakhmanov 1962). A tincture of the aboveground parts had low toxicity, hemostatic and sedative properties similar to those of L. inebrians, and hypotensive effects which surpassed those of L inebrians. Clinical tests established the efficacy of the tincture for the treatment of hypertonic illness and as a hemostatic. A tincture of leaves and flowers exhibited hypotensive and sedative effects, and increased the speed of blood coagulation without increase of the prothrombin time (Alimbaeva 1961). 

Documented effects This species is used to treat infectious diseases, hemorrhagic diathesis, gastritis (particularly with low acidity), and is used as a tonic to treat the cardio-vascular system (Akopov 1990). An extract of the fruits has shown antiviral activity against herpes and influenza A and B viruses (Knox et al. 2001,2003 Suzutani et al. 2003). Proanthocyanidins isolated from the leaves exhibit anti-inflanunatory effects in rats (Garbacki et al. 2004). 

The nature of substituents in position 8 of flnoroquinolones also makes a certain impact on antibacterial activity. The key role of the 8-methoxy substituent is demonstrated by the fact that this fragment is a part of such effective drugs, as moxifioxacin and gatifioxacin [176-180]. Indeed, fluoroquinolone 52 shows a high activity against H. influenza and M. catarrhalis [181], while compound 53 is 4 times more active against S. pneumoniae than levofloxacin [182, 183], 8-Methoxy-6-fluoroquinolone 54 has smaller side effects on the cardio-vascular system, than gatifioxacin (Scheme 24) [184],... 

Inspite of all the qualified successes of synthetic drug research achieved in the last four decades to combat infectious diseases of the more than 80,000 different ailments, unfortunately only about one third can be treated with drugs, most of them only symptomatically. The discovery of better, effective and safer drugs is needed to fight the causes of dreadful diseases like cancer, acquired-immuno-deficiency-syndrome (AIDS), arthritis, cardio-vascular diseases, disorders of the central nervous system (CNS), such as Alzheimer s disease and other vital infectious and metabolic diseases like rheumatoid arthritis. 

Describes the effects of CWAs on human tissue and dermal, neuro-, cardio-, vascular, and reproductive systems... 

Mechanisms underlying the extra-pulmonary cardio-vascular or systemic effects are incompletely understood. However, pulmonary inflammation can lead to systemic inflammation and pulmonary reflexes can activate the autonomic nervous system. Many animal studies confirm the systemic cardiovascular toxicity... 

Refers to the heart (cardio) and blood vessels (vascular) and the system for distributing blood, oxygen and nutrients to various tissues... 

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