Carcinogenic effects population studies

Cancer. No studies were located regarding carcinogenic effects of cyanide exposure in humans or animals following any route of exposure. Therefore, no hypothesis can be made as to whether or not an increased risk of cancer can be expected in populations exposed to cyanide. 

Epidemiological studies of methyl mercury-exposed populations have not shown any evidence of a carcinogenic effect. In chronic animal studies, methyl mercury chloride in the diet caused an increase in renal... 

The effects of PCBs alone on reproduction and development, as well as their carcinogenic effects, have yet to be established in humans—whether workers or the general population—even though some subjects have been exposed to very high levels of PCBs. Some adverse behavioral effects in infants are reported to have been observed in two studies involving subjects from the general population, but the adverse effects observed in the two studies were dissimilar furthermore, there are a number of uncertainties about the exposure assessments in both studies (Kimbrough, 1995). 

Mineral Oil Hydraulic Fluids. There is limited information on the toxicity of mineral oil hydraulic fluids in humans. A single case report of a child accidentally ingesting a single dose of automotive transmission fluid provides limited information on death and systemic effects. A case-control study provides some information on the carcinogenicity of mineral oil hydraulic fluids. The study population was exposed via inhalation and dermal routes. An occupational exposure study provides information on neurotoxicity following chronic dermal exposure. Information on the toxicity of mineral oil hydraulic fluids is limited to a series of inhalation, oral, and dermal acute-duration exposures. These studies provide information on death, systemic effects, and neurotoxicity by inhalation, oral, and dermal routes, and immunotoxicity following dermal exposure. 

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