Cannabinoid receptor binding

Berrendero, F., Sepe, N., Ramos, J. A., Di Marzo, V., and Femandez-Ruiz, J. J. (1999). Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period. Synapse 33, 181—191. [Pg.129]

Westlake TM, Howlett AC, Bonner II, Matsuda LA, Herkenham M. 1994. Cannabinoid receptor binding and messenger RNA expression in human brain An in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer s brains. Neuroscience 63 637-652. [Pg.491]

Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR (1995) Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. J Pharmacol Exp Ther 273 1172-1181... [Pg.39]

Abood ME, Sauss C, Fan F, Tilton CL, Martin BR (1993) Development ofbehavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain. Pharmacol Biochem Behav 46 575-579... [Pg.69]

Melvin LS, Milne GM, Johnson MR, Subramaniam B, Wilken GH, Howlett AC (1993) Structure-activity relationships for cannabinoid receptor-binding and analgesic activity studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015... [Pg.75]

Oviedo A, Glowa J, Herkenham M (1993) Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain a quantitative autoradiographic study. Brain Res 616 293-302... [Pg.75]

Pinto JC, Potie F, Rice KC, Boring D, Johnson MR, Evans DM, Wilken GH, Cantrell CH, Howlett AC (1994) Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid. Mol Pharmacol 46 516-522... [Pg.76]

Romero J, Garcia-Palomero E, Castro JG, Garcia-Gil L, Ramos JA, Fernandez-Ruiz JJ (1997) Effects of chronic exposure to delta9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions. Brain Res Mol Brain Res 46 100-108... [Pg.76]

Hungund BL, Basavarajappa BS (2000) Distinct differences in the cannabinoid receptor binding in the brain of C57BL/6 and DBA/2 mice, selected for their differences in voluntary ethanol consumption. J Neurosci Res 60 122-128... [Pg.110]

Mailleux P, Vanderhaeghen JJ (1992b) Age-related loss of cannabinoid of cannabinoid receptor binding sites and mRNA in the rat striatum. Neurosci Lett 147 179-181... [Pg.504]

The presence of endocannabinoids has been shown in the hypothalamus (Herkenham 1995) and in the anterior pituitary (Gonzales 1999). The central cannabinoid receptor (CBi receptor) is also present is these structures. The hypothalamus contains fewer cannabinoid binding sites than other areas of the CNS. Nevertheless the effects caused by the activation of CBi receptors in the hypothalamus are important, maybe because the receptors are more or less concentrated within specific hypothalamic nuclei-areas (Fig. 2). CBi receptors seem to be located on intrinsic hypothalamic neurons rather than on neurons with cell bodies located outside the hypothalamus, since hypothalamic deafferentation is not followed by any reduction in the number of cannabinoid receptor binding sites within this brain area (Romero 1998). [Pg.557]

Romero J, Wenger T, deMiguel R, Ramos JA, Fernandez-Ruiz JJ (1998) Cannabinoid receptor binding did not vary in several hypothalamic nuclei after hypothalamic deafferentation. Life Sci 63 351-356... [Pg.570]

Wise ML, Soderstrom K, Murray TF, and Gerwick WH (1996) Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. Experientia 52 88-92. [Pg.53]

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