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Cancer histone modifying enzymes

Zhang K, Dent SY (2005) Histone modifying enzymes and cancer Going beyond histones. J Cell Biochem 96 1137-1148... [Pg.428]

Among the histone modifying enzymes, HATs and HDACs are the best characterized biochemically and provide attractive opportunities for interdisciplinary research between chemists and biologists. At present, the HDACs have outstripped the HATs in terms of their impact on drug discovery. Multiple HDAC inhibitors from several chemical classes are currently in clinical trials for cancer chemotherapy, whereas the literature on HAT inhibitors is limited to in vitro data. [Pg.696]

Santos-rosa H, Caldas C (2005) Chromatin modifier enzymes, the histone code and cancer. Eur J Cancer 41 2381-2402... [Pg.348]

Gibbons RJ (2005) Histone modifying and chromatin remodelling enzymes in cancer and dysplastic syndromes. Hum Mol Genet 14 R85-92... [Pg.366]

See other pages where Cancer histone modifying enzymes is mentioned: [Pg.40]    [Pg.397]    [Pg.407]    [Pg.24]    [Pg.269]    [Pg.316]    [Pg.460]    [Pg.1]    [Pg.410]    [Pg.291]    [Pg.579]    [Pg.406]    [Pg.406]    [Pg.6]    [Pg.159]   


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Histone-modifying enzyme

Modified Enzymes

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