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Histone cancer

Gallinari P, Di Marco S, Pallaro M et al (2007) HDACS, histone deacetylation and gene transcription from molecular biology to cancer therapeutics. Cell Res 17 195-211... [Pg.595]

In addition to histone deacetylation, histone lysine methylation can also lead to gene silencing which is not blocked by the HDAC inhibitors [6, 51], Several lines of evidence have suggested a connection between cancer and histone lysine methyltrans-ferases (HKMTs) [52], HKMTs catalyze the transfer of methyl group(s) from the cofactor. S -adenosyI-methionine (AdoMet) to some specific lysine residues in the N-terminal histone tails [53, 54], With one exception of Dotl [55], all known HKMTs contain the SET domain which represents a novel structural fold [53, 56], Among SET-domain HKMTs, SET7/9 is one of the best characterized experimentally. It is a... [Pg.345]

Hake SB, Xiao A, Allis CD (2004) Linking the epigenetic language of covalent histone modifications to cancer. Br J Cancer 90 761-769... [Pg.348]

Santos-rosa H, Caldas C (2005) Chromatin modifier enzymes, the histone code and cancer. Eur J Cancer 41 2381-2402... [Pg.348]

Marks PA, Rifkind RA, Richon VM, Breslow R, Miller T, Kelly WK (2001) Histone deacetylases and cancer causes and therapies. Nat Rev Cancer 1 194-202... [Pg.350]

Schneider R, Bannister AJ, Kouzarides T (2002) Unsafe sets histone lysine methyltransferases and cancer. Trends Biochem Sci 27 396-402... [Pg.350]

Vigushin DM, Coombes RC (2002) Histone deacetylase inhibitors in cancer treatment. Anticancer Drugs 13 1... [Pg.61]

Pray-Grant MG, Daniel JA, Schieltz D, Yates JR, 3rd, Grant PA (2005) Chdl chromodomain links histone H3 methylation with SAGA- and SLlK-dependent acetylation. Nature 433 434-438 Rando OJ, Zhao K, Janmey P, Crabtree GR (2002) Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-hke BAF chromatin remodehng complex. Proc Natl Acad Sci USA 99 2824-2829 Roberts CW, Orkin SH (2004) The SWI/SNF complex - chromatin and cancer. Nat Rev Cancer 4 133-142... [Pg.43]

HISTONE VARIANTS AND DISEASE 6.1. Histone Variants and Cancer... [Pg.82]

Sedelnikova OA, Pilch DR, Redon C, Bonner WM (2003) Histone H2AX in DNA damage and repair. Cancer Biol Ther 2 233-235... [Pg.108]

Polo SE, Almouzni G (2005). Histone metabolic pathways and chromatin assembly factors as proliferation markers Cancer Lett 220 1-9... [Pg.123]


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See also in sourсe #XX -- [ Pg.268 ]




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